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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHLKKGKRSI STVWRLLWKR FYSVNSKTNM HFSRSRKKPV TNFTRTNGLL LSCNGDTFPY

70 80 90 100 110 120
LRTLWRYFNA PGNLMFVTTN IVAFMGIVTY NTLVTISSER AFEEQMMAAQ VSLAKQREEL

130 140 150 160 170 180
ETTALSLPRD IELRGEEDDI KWEQPDVAHV REDPLVEEQN AKLDTPIKQY TLGDLILNKR

190 200 210 220 230 240
ENVTDYDSQR AKASIFHMLY AYMLYRDVIQ PTTMTQNNNS EEWRREVELL TKGKEVQGTH

250 260 270 280 290 300
RRIDVFYDLW NKNFDKIVTS PEKVQNFQLP NWSKYPTILK FICTELHDNS LKTLGEFKQF

310 320 330 340 350 360
YGKVRSNEVK KLLGLWLYDH SFLFPHNIYD NRTEEDFYDI LINDSMQDNR IFQKYSSIVM

370 380 390 400 410 420
NPYNERTQLF FPNVNSPSVN KPVPSISLET YTRLLKGYIN LQETGCKYDY NDNIFKLISI

430 440 450 460 470 480
LKLNCFLQRN KKKHAGPTVR ILLPRDEDRS QILGTISQAE KRTCYQILSK NRDVVALLKR


ISDIQADSS


References and documentation are available.

Number of amino acids: 489 Molecular weight: 57487.69 Theoretical pI: 9.14
Amino acid composition: 
Ala (A) 16 3.3% Arg (R) 32 6.5% Asn (N) 36 7.4% Asp (D) 28 5.7% Cys (C) 5 1.0% Gln (Q) 22 4.5% Glu (E) 30 6.1% Gly (G) 16 3.3% His (H) 9 1.8% Ile (I) 30 6.1% Leu (L) 51 10.4% Lys (K) 37 7.6% Met (M) 11 2.2% Phe (F) 23 4.7% Pro (P) 19 3.9% Ser (S) 33 6.7% Thr (T) 34 7.0% Trp (W) 8 1.6% Tyr (Y) 22 4.5% Val (V) 27 5.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 58 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 2578 Hydrogen H 4042 Nitrogen N 706 Oxygen O 753 Sulfur S 16 Formula: C2578H4042N706O753S16 Total number of atoms: 8095 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 77030 Abs 0.1% (=1 g/l) 1.340, assuming all pairs of Cys residues form cystines Ext. coefficient 76780 Abs 0.1% (=1 g/l) 1.336, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.40 This classifies the protein as unstable. Aliphatic index: 83.89 Grand average of hydropathicity (GRAVY): -0.567