ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHRTYSLRNQ RAPTAAELQA PPPPPSSTKS KFFGKASIAS SFRKNAAGNF GPELARKLSQ 

        70         80         90        100        110        120 
LVKTEKGVLR AMEVVASERR EAAKQLSLWG ADNDDDVSDV TDKLGVLIYE LGELQDQFID 

       130        140        150        160        170        180 
KYDQYRVTLK SIRNIEASVQ PSRDRKEKIT DEIAHLKYKD PQSTKIPVLE QELVRAEAES 

       190        200        210        220        230        240 
LVAEAQLSNI TREKLKAAYS YMFDSLRELS EKFALIAGYG KALLELLDDS PVTPGEARPA 

       250        260        270        280        290        300 
YDGYEASRQI IMDAESALES WTLDMAAVKP TLSFHQTVDD VYEDEDGEEE EEPEIQNGDI 

       310        320        330        340 
PGQVVEEEEV EWTTEVPVDD EAHEADHHVS QNGHTSGSEN I 

References and documentation are available.

Number of amino acids: 341

Molecular weight: 38071.16

Theoretical pI: 4.62

Amino acid composition: 
Ala (A)  34	 10.0%
Arg (R)  17	  5.0%
Asn (N)   9	  2.6%
Asp (D)  26	  7.6%
Cys (C)   0	  0.0%
Gln (Q)  16	  4.7%
Glu (E)  41	 12.0%
Gly (G)  16	  4.7%
His (H)   7	  2.1%
Ile (I)  15	  4.4%
Leu (L)  29	  8.5%
Lys (K)  21	  6.2%
Met (M)   5	  1.5%
Phe (F)   8	  2.3%
Pro (P)  17	  5.0%
Ser (S)  28	  8.2%
Thr (T)  16	  4.7%
Trp (W)   3	  0.9%
Tyr (Y)  11	  3.2%
Val (V)  22	  6.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 67
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      1665
Hydrogen    H	      2623
Nitrogen    N	       455
Oxygen      O	       556
Sulfur      S	         5

Formula: C1665H2623N455O556S5
Total number of atoms: 5304

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32890
Abs 0.1% (=1 g/l)   0.864

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.07
This classifies the protein as unstable.



Aliphatic index: 79.00

Grand average of hydropathicity (GRAVY): -0.656