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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHSGKRPLSP ESMAGNREEK KELCCCSTLS ESDVSDFVSE LTGQPIPSSI DDQSSSLTLQ

70 80 90 100 110 120
EKSNSRQRNY RGVRQRPWGK WAAEIRDPNK AARVWLGTFD TAEEAALAYD KAAFEFRGHK

130 140 150 160 170 180
AKLNFPEHIR VNPTQLYPSP ATSHDRIIVT PPSPPPPIAP DILLDQYGHF QSRSSDSSAN

190 200 210
LSMNMLSSSS SSLNHQGLRP NLEDGENVKN ISIHKRRK


References and documentation are available.

Number of amino acids: 218 Molecular weight: 24297.08 Theoretical pI: 8.43
Amino acid composition: 
Ala (A) 15 6.9% Arg (R) 16 7.3% Asn (N) 12 5.5% Asp (D) 12 5.5% Cys (C) 3 1.4% Gln (Q) 9 4.1% Glu (E) 14 6.4% Gly (G) 10 4.6% His (H) 7 3.2% Ile (I) 10 4.6% Leu (L) 17 7.8% Lys (K) 12 5.5% Met (M) 4 1.8% Phe (F) 6 2.8% Pro (P) 18 8.3% Ser (S) 31 14.2% Thr (T) 8 3.7% Trp (W) 3 1.4% Tyr (Y) 4 1.8% Val (V) 7 3.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 26 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 1050 Hydrogen H 1662 Nitrogen N 316 Oxygen O 335 Sulfur S 7 Formula: C1050H1662N316O335S7 Total number of atoms: 3370 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 22585 Abs 0.1% (=1 g/l) 0.930, assuming all pairs of Cys residues form cystines Ext. coefficient 22460 Abs 0.1% (=1 g/l) 0.924, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 70.87 This classifies the protein as unstable. Aliphatic index: 64.50 Grand average of hydropathicity (GRAVY): -0.821