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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHWNIISKEQ SSSSVSLPTL DSSEPCHIEV ILRAIPEKGL QNNESTFKID PYENTVLFRT

70 80 90 100 110 120
NNPLHETTKE THSTFQFDKV FDANATQEDV QKFLVHPIIN DVLNGYNGTV ITYGPSFSGK

130 140 150 160 170 180
SYSLIGSKES EGILPNICKT LFDTLEKNEE TKGDSFSVSV LAFEIYMEKT YDLLVPLPER

190 200 210 220 230 240
KPLKLHRSSS KMDLEIKDIC PAHVGSYEDL RSYIQAVQNV GNRMACGDKT ERSRSHLVFQ

250 260 270 280 290 300
LHVEQRNRKD DILKNSSLYL VDLHGAEKFD KRTESTLSQD ALKKLNQSIE ALKNTVRSLS

310 320 330 340 350 360
MKERDSAYSA KGSHSSAYRE SQLTEVLKDS LGGNRKTKVI LTCFLSNVPT TLSTLEFGDS

370 380 390 400 410 420
IRQINNKVTD NTTGLNLKKK MDLFIQDMKI KDDNYVAQIN ILKAEIDSLK SLHNKSLPED

430 440 450 460 470 480
DEKKMLENTK KENIKLKLQL DSITQLLSSS TNEDPNNRID EEVSEILTKR CEQIAQLELS

490 500 510 520 530 540
FDRQMNSNSK LQQELEYKKS KEEALESMNV RLLEQIQLQE REIQELLTTN AILKGELETH

550 560 570 580 590 600
TKLTETRSER IKSLESSVKE LSLNKSAIPS PRRGSMSSSS GNTMLHIEEG SEISNSPWSA

610 620 630 640 650
NTSSKPLVWG ARKVSSSSIA TTGSQESFVA RPFKKGLNLH SIKVTSSTPK SPSSGS


References and documentation are available.

Number of amino acids: 656 Molecular weight: 73799.23 Theoretical pI: 6.48
Amino acid composition: 
Ala (A) 23 3.5% Arg (R) 27 4.1% Asn (N) 41 6.2% Asp (D) 33 5.0% Cys (C) 6 0.9% Gln (Q) 27 4.1% Glu (E) 58 8.8% Gly (G) 25 3.8% His (H) 15 2.3% Ile (I) 40 6.1% Leu (L) 72 11.0% Lys (K) 60 9.1% Met (M) 12 1.8% Phe (F) 18 2.7% Pro (P) 22 3.4% Ser (S) 87 13.3% Thr (T) 44 6.7% Trp (W) 3 0.5% Tyr (Y) 13 2.0% Val (V) 30 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 91 Total number of positively charged residues (Arg + Lys): 87 Atomic composition: Carbon C 3211 Hydrogen H 5220 Nitrogen N 898 Oxygen O 1051 Sulfur S 18 Formula: C3211H5220N898O1051S18 Total number of atoms: 10398 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36245 Abs 0.1% (=1 g/l) 0.491, assuming all pairs of Cys residues form cystines Ext. coefficient 35870 Abs 0.1% (=1 g/l) 0.486, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 54.16 This classifies the protein as unstable. Aliphatic index: 83.35 Grand average of hydropathicity (GRAVY): -0.634