ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHYCVLRTFL LLHLVPVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP 

        70         80         90        100        110        120 
DEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPS HFPSESKYSF 

       130 
RGFRLFRTRV 

References and documentation are available.

Number of amino acids: 130

Molecular weight: 15251.54

Theoretical pI: 7.72

Amino acid composition: 
Ala (A)   7	  5.4%
Arg (R)  13	 10.0%
Asn (N)   1	  0.8%
Asp (D)   7	  5.4%
Cys (C)   3	  2.3%
Gln (Q)   3	  2.3%
Glu (E)  12	  9.2%
Gly (G)   2	  1.5%
His (H)   3	  2.3%
Ile (I)   6	  4.6%
Leu (L)  14	 10.8%
Lys (K)   7	  5.4%
Met (M)   4	  3.1%
Phe (F)   6	  4.6%
Pro (P)   9	  6.9%
Ser (S)  13	 10.0%
Thr (T)   6	  4.6%
Trp (W)   0	  0.0%
Tyr (Y)   7	  5.4%
Val (V)   7	  5.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 19
Total number of positively charged residues (Arg + Lys): 20

Atomic composition:

Carbon      C	       679
Hydrogen    H	      1074
Nitrogen    N	       186
Oxygen      O	       199
Sulfur      S	         7

Formula: C679H1074N186O199S7
Total number of atoms: 2145

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10555
Abs 0.1% (=1 g/l)   0.692, assuming all pairs of Cys residues form cystines


Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.684, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 71.31
This classifies the protein as unstable.



Aliphatic index: 81.00

Grand average of hydropathicity (GRAVY): -0.467