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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIATSRAVNM NKESKHKKAV AKPCRERQTS VTRAMRPAVA RDPRRLSTSS SPSSSPMSAQ

70 80 90 100 110 120
RRLSREEIIN EMEKEQDAIV VRLLREIETL KEENSRLKNQ LHHPVPARRS SPFFEGESAI

130 140 150 160 170 180
LDDDDCNYGY TLDTPKLKLT DGASRHTVLP LTPKDSMTHI SHSARRSSRN ASISNGTSIS

190 200 210 220 230 240
DTIFPIETKI HSAPTTNRNL PSADLPHHTL LPRSLSGISS SDLTESGALL HDRRRRSSNY

250 260
SLDGSNSLKA DLMAKRFQTG SLK


References and documentation are available.

Number of amino acids: 263 Molecular weight: 29262.94 Theoretical pI: 9.99
Amino acid composition: 
Ala (A) 19 7.2% Arg (R) 27 10.3% Asn (N) 12 4.6% Asp (D) 15 5.7% Cys (C) 2 0.8% Gln (Q) 5 1.9% Glu (E) 15 5.7% Gly (G) 8 3.0% His (H) 10 3.8% Ile (I) 13 4.9% Leu (L) 25 9.5% Lys (K) 15 5.7% Met (M) 7 2.7% Phe (F) 4 1.5% Pro (P) 16 6.1% Ser (S) 40 15.2% Thr (T) 19 7.2% Trp (W) 0 0.0% Tyr (Y) 3 1.1% Val (V) 8 3.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 30 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 1241 Hydrogen H 2058 Nitrogen N 396 Oxygen O 403 Sulfur S 9 Formula: C1241H2058N396O403S9 Total number of atoms: 4107 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 4595 Abs 0.1% (=1 g/l) 0.157, assuming all pairs of Cys residues form cystines Ext. coefficient 4470 Abs 0.1% (=1 g/l) 0.153, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 68.89 This classifies the protein as unstable. Aliphatic index: 72.40 Grand average of hydropathicity (GRAVY): -0.775