ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIESLRLLAQ HKSFTELLLS STLINVLSLA LPFTMLQIYD RILPNEAYGT ASVLAIGVGI 

        70         80         90        100        110        120 
AILLELVLRY TRSWLLALNA SNYELQTTAQ FVDRLMKADY HHVEQLGSGK ILHGITSIAT 

       130        140        150        160        170        180 
MREIYSGQAA VALMDFPFVI IFLALVAYIG GPLVFIPILV WGIAGIGVWQ IGKKLSVATR 

       190        200        210        220        230        240 
ELAISDDERT RLLILVLSGL TTAKSLALES RITYAYKKIN YQRLAQQNEV DWLSSQLQEW 

       250        260        270        280        290        300 
IQGASQATTL ALVLIGCFEV LNGDLTTGGL AACSILAGRA VAPLSAIGSL KAKFVTAQSA 

       310        320        330        340        350        360 
MQDVNEIIAS PPESLNGTQV YQQKLPSGPI QFEQVSAQQT GAKLKQINLT IPAGSLVTVT 

       370        380        390        400        410        420 
SNPLTHASLL LSTVGGYHQV TEGAIKIDSI PLTEHDPLEY RQSISYVSPW ATLLAGSILD 

       430        440        450        460        470        480 
NLTLFRHERE AYAMVLADKL GLSATIAQLP AGYQTLVGNN DSQMLNKGAI KLIAIVRALA 

       490        500        510        520        530        540 
QSPSILLLDE PMVSLDADSQ QRLLALLLEL KNHITLIVAS YFTEIAAISD YRIHISSQGD 


ATMSSNGEL 

References and documentation are available.

Number of amino acids: 549

Molecular weight: 59421.95

Theoretical pI: 5.73

Amino acid composition: 
Ala (A)  59	 10.7%
Arg (R)  18	  3.3%
Asn (N)  17	  3.1%
Asp (D)  19	  3.5%
Cys (C)   2	  0.4%
Gln (Q)  33	  6.0%
Glu (E)  25	  4.6%
Gly (G)  35	  6.4%
His (H)  10	  1.8%
Ile (I)  48	  8.7%
Leu (L)  86	 15.7%
Lys (K)  18	  3.3%
Met (M)  10	  1.8%
Phe (F)  12	  2.2%
Pro (P)  18	  3.3%
Ser (S)  48	  8.7%
Thr (T)  35	  6.4%
Trp (W)   6	  1.1%
Tyr (Y)  18	  3.3%
Val (V)  32	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      2687
Hydrogen    H	      4343
Nitrogen    N	       697
Oxygen      O	       789
Sulfur      S	        12

Formula: C2687H4343N697O789S12
Total number of atoms: 8528

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    59945
Abs 0.1% (=1 g/l)   1.009, assuming all pairs of Cys residues form cystines


Ext. coefficient    59820
Abs 0.1% (=1 g/l)   1.007, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.45
This classifies the protein as stable.



Aliphatic index: 122.84

Grand average of hydropathicity (GRAVY): 0.354