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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIGAVNSVEA VITSIQGLSG SPEDLSALHD LLRGAQDSLR AEPGVNFSTL DQLDASKHSL

70 80 90 100 110 120
GYLYFLEVLT CGPVSKEKAA YEIPIIARFI NSCDAGQIRL ASYKFVSLCK ILKDHVIALG

130 140 150 160 170 180
DPLRGVGPLL NAVQKLQVSS KRLTALHPDV LQLCLQAKSY KSGFSILSDD IVEIDQPRDF

190 200 210 220 230 240
FLYSYYGGMI CIGLKRFQKA LELLYNVVTA PMHQVNAIAL EAYKKYILVS LIHNGQFTNT

250 260 270 280 290 300
LPKCASTAAQ RSFKNYTGPY IELGNCYNDG KIGELEALVV ARNAEFEEDK NLGLVKQAVS

310 320 330 340 350 360
SLYKRNILRL TQKYLTLSLQ DIANMVQLGN AKEAEMHVLQ MIQDGQIHAL INQKDGMVRF

370 380 390 400 410 420
LEDPEQYKSS EMIEIMDSVI QRTIGLSKNL LAMDESLSCD PLYLGKVGRE RQRYDFGDDF


DTVPQKFSM


References and documentation are available.

Number of amino acids: 429 Molecular weight: 47741.03 Theoretical pI: 5.96
Amino acid composition: 
Ala (A) 32 7.5% Arg (R) 17 4.0% Asn (N) 18 4.2% Asp (D) 26 6.1% Cys (C) 8 1.9% Gln (Q) 25 5.8% Glu (E) 23 5.4% Gly (G) 28 6.5% His (H) 8 1.9% Ile (I) 29 6.8% Leu (L) 56 13.1% Lys (K) 27 6.3% Met (M) 11 2.6% Phe (F) 15 3.5% Pro (P) 14 3.3% Ser (S) 33 7.7% Thr (T) 13 3.0% Trp (W) 0 0.0% Tyr (Y) 19 4.4% Val (V) 27 6.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 2131 Hydrogen H 3406 Nitrogen N 566 Oxygen O 636 Sulfur S 19 Formula: C2131H3406N566O636S19 Total number of atoms: 6758 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28810 Abs 0.1% (=1 g/l) 0.603, assuming all pairs of Cys residues form cystines Ext. coefficient 28310 Abs 0.1% (=1 g/l) 0.593, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.36 This classifies the protein as stable. Aliphatic index: 102.98 Grand average of hydropathicity (GRAVY): -0.061