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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIGGFNSDMK EHIRRANKGE IHCHFPSHKS QNELTELLAN DTKMMILKKI KDAKYFSVIL

70 80 90 100 110 120
DSIPDVSRKE QMTFLIRCVD VSTCSPKIEE FFLTFLHIKD KREYTDNPGH RSDVESLTES

130 140 150 160 170 180
ETHGIGGFEF LFGMIIWYDL LAAVNIVSKS LQFEDMDLEV AISQLGGLVT YLKNYKETGF

190 200 210 220 230 240
EKAKVESTQI AIEMKIAPVF PKKSVKKKKQ FVEDVEKIDE SKIAEESFRI DYFINIMDQA

250 260 270 280 290 300
IMCIEIRFEQ FQVYEQIFGF LFGVKRLKVA EDDELRTSCM KLEASLKHDV HSDVDGEDLF

310 320 330 340 350 360
MELKLLKDVL PKEITKPVEV LKFLKIMDSC YPNTWIAYRI LLTIPVSVAL AERTFSKLKL

370 380
IKKYLRSTMS QERLNGLALI SV


References and documentation are available.

Number of amino acids: 382 Molecular weight: 44120.45 Theoretical pI: 6.07
Amino acid composition: 
Ala (A) 17 4.5% Arg (R) 14 3.7% Asn (N) 10 2.6% Asp (D) 24 6.3% Cys (C) 6 1.6% Gln (Q) 11 2.9% Glu (E) 35 9.2% Gly (G) 15 3.9% His (H) 9 2.4% Ile (I) 34 8.9% Leu (L) 38 9.9% Lys (K) 40 10.5% Met (M) 14 3.7% Phe (F) 24 6.3% Pro (P) 10 2.6% Ser (S) 27 7.1% Thr (T) 17 4.5% Trp (W) 2 0.5% Tyr (Y) 10 2.6% Val (V) 25 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 54 Atomic composition: Carbon C 1997 Hydrogen H 3179 Nitrogen N 505 Oxygen O 576 Sulfur S 20 Formula: C1997H3179N505O576S20 Total number of atoms: 6277 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 26275 Abs 0.1% (=1 g/l) 0.596, assuming all pairs of Cys residues form cystines Ext. coefficient 25900 Abs 0.1% (=1 g/l) 0.587, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.72 This classifies the protein as unstable. Aliphatic index: 96.94 Grand average of hydropathicity (GRAVY): -0.147