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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MILRLKDQTL IKINSTRSYL SSLVFRRDSH SQARTKPDHD RRRRGYERDV RIEEKKEHDG

70 80 90 100 110 120
LFLCKSKGQH LLTNTRILDS IVRSSDIRPT DTVLEIGPGT GNLTMKLLEA AQNVVAVELD

130 140 150 160 170 180
KRMVEILRKR VSDHGFADKL TIIQKDVLKT DFPHFDLVVA NIPYNISSPL VAKLVYGSNT

190 200 210 220 230 240
FRSATLLLQK EFSRRLLANP GDSDFNRLAV NVKLVADVKF VMDVSKREFV PPPKVDSSVI

250 260 270 280 290 300
RITPKEIIPD VNVQEWLAFT RTCFGKKNKT LGSMFRQKKK VMELQSLSAG RHGSNVEVMN

310 320 330 340 350 360
QTGGDSDSDV EEDGKDDLLC LDTDASMFKE RVIEILRTNG FEEKRPSKLS HRELLHLLSL

370 380
FNQAGIFFHD ITSLQMDLHE


References and documentation are available.

Number of amino acids: 380 Molecular weight: 43314.78 Theoretical pI: 9.15
Amino acid composition: 
Ala (A) 15 3.9% Arg (R) 30 7.9% Asn (N) 16 4.2% Asp (D) 31 8.2% Cys (C) 3 0.8% Gln (Q) 12 3.2% Glu (E) 22 5.8% Gly (G) 18 4.7% His (H) 11 2.9% Ile (I) 21 5.5% Leu (L) 44 11.6% Lys (K) 30 7.9% Met (M) 9 2.4% Phe (F) 18 4.7% Pro (P) 13 3.4% Ser (S) 31 8.2% Thr (T) 21 5.5% Trp (W) 1 0.3% Tyr (Y) 4 1.1% Val (V) 30 7.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 1910 Hydrogen H 3111 Nitrogen N 551 Oxygen O 571 Sulfur S 12 Formula: C1910H3111N551O571S12 Total number of atoms: 6155 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 11585 Abs 0.1% (=1 g/l) 0.267, assuming all pairs of Cys residues form cystines Ext. coefficient 11460 Abs 0.1% (=1 g/l) 0.265, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.13 This classifies the protein as unstable. Aliphatic index: 93.55 Grand average of hydropathicity (GRAVY): -0.407