ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MINCKVIENR RTRFFPLVNA KLVKVIASSL INKFQSLPLA MSKLFSTVNS ARHSVPLGGM 

        70         80         90        100        110        120 
RDYVHIKKLE MNTVLGPDSW NQLMPQKCLL SLDMGTDFSK SAATDDLKYS LNYAVISRDL 

       130        140        150        160        170        180 
TNFVSKKKNW GSVSNLAKSV SQFVMDKYSG VECLNLEVQA DTTHIRSDHI SCIIQQERGN 

       190        200        210        220        230        240 
PESQEFDVVR ISELKMLTLI GVFTFERLKK QYVTLDIKLP WPKKAELPPP VQSIIDNVVK 

       250        260        270        280        290        300 
FVEESNFKTV EALVESVSAV IAHNEYFQKF PDSPLVVKVL KLNAITATEG VGVSCIREPR 

       310        320        330        340        350        360 
EIAMVNIPYL SSIHESSDIK FQLSSSQNTP IEGKNTWKRA FLAFGSNIGD RFKHIQMALQ 

       370        380        390        400        410        420 
LLSREKTVKL RNISSIFESE PMYFKDQTPF MNGCVEVETL LTPSELLKLC KKIEYEELQR 

       430        440        450        460        470        480 
VKHFDNGPRT IDLDIVMFLN SAGEDIIVNE PDLNIPHPRM LERTFVLEPL CELISPVHLH 

       490        500        510        520        530        540 
PVTAEPIVDH LKQLYDKQHD EDTLWKLVPL PYRSGVEPRF LKFKTATKLD EFTGETNRIT 

       550        560        570        580        590        600 
VSPTYIMAIF NATPDSFSDG GEHFADIESQ LNDIIKLCKD ALYLHESVII DVGGCSTRPN 

       610        620        630        640        650        660 
SIQASEEEEI RRSIPLIKAI RESTELPQDK VILSIDTYRS NVAKEAIKVG VDIINDISGG 

       670        680        690        700        710        720 
LFDSNMFAVI AENPEICYIL SHTRGDISTM NRLAHYENFA LGDSIQQEFV HNTDIQQLDD 

       730        740        750        760        770        780 
LKDKTVLIRN VGQEIGERYI KAIDNGVKRW QILIDPGLGF AKTWKQNLQI IRHIPILKNY 

       790        800        810        820        830        840 
SFTMNSNNSQ VYVNLRNMPV LLGPSRKKFI GHITKDVDAK QRDFATGAVV ASCIGFGSDM 

       850        860 
VRVHDVKNCS KSIKLADAIY KGLE 

References and documentation are available.

Number of amino acids: 864

Molecular weight: 97675.50

Theoretical pI: 6.43

Amino acid composition: 
Ala (A)  42	  4.9%
Arg (R)  38	  4.4%
Asn (N)  48	  5.6%
Asp (D)  52	  6.0%
Cys (C)  13	  1.5%
Gln (Q)  32	  3.7%
Glu (E)  56	  6.5%
Gly (G)  38	  4.4%
His (H)  21	  2.4%
Ile (I)  75	  8.7%
Leu (L)  81	  9.4%
Lys (K)  64	  7.4%
Met (M)  20	  2.3%
Phe (F)  39	  4.5%
Pro (P)  40	  4.6%
Ser (S)  70	  8.1%
Thr (T)  42	  4.9%
Trp (W)   7	  0.8%
Tyr (Y)  20	  2.3%
Val (V)  66	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 108
Total number of positively charged residues (Arg + Lys): 102

Atomic composition:

Carbon      C	      4371
Hydrogen    H	      6973
Nitrogen    N	      1171
Oxygen      O	      1293
Sulfur      S	        33

Formula: C4371H6973N1171O1293S33
Total number of atoms: 13841

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    69050
Abs 0.1% (=1 g/l)   0.707, assuming all pairs of Cys residues form cystines


Ext. coefficient    68300
Abs 0.1% (=1 g/l)   0.699, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.42
This classifies the protein as unstable.



Aliphatic index: 97.43

Grand average of hydropathicity (GRAVY): -0.191