ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MINEILQKSE KKMAASLDVL SQELSGIRTG RSSPALVEHI KVEYAGVPTP INHLASIAAP 

        70         80         90        100        110        120 
DPRYITIQPW DRSCLSAIEK AIMKSDLGLM PNNDGNIIRL NIPPLSEERR QEMIKMVSKR 

       130        140        150        160        170        180 
LEEDKIAMRN VRRDAMDEMK KLEKSKEISQ DDLKRGSDQL QKITDSFIAK ADKLGADKET 


ELKQV 

References and documentation are available.

Number of amino acids: 185

Molecular weight: 20868.13

Theoretical pI: 7.78

Amino acid composition: 
Ala (A)  14	  7.6%
Arg (R)  12	  6.5%
Asn (N)   7	  3.8%
Asp (D)  14	  7.6%
Cys (C)   1	  0.5%
Gln (Q)   8	  4.3%
Glu (E)  16	  8.6%
Gly (G)   7	  3.8%
His (H)   2	  1.1%
Ile (I)  18	  9.7%
Leu (L)  17	  9.2%
Lys (K)  19	 10.3%
Met (M)   9	  4.9%
Phe (F)   1	  0.5%
Pro (P)   9	  4.9%
Ser (S)  16	  8.6%
Thr (T)   5	  2.7%
Trp (W)   1	  0.5%
Tyr (Y)   2	  1.1%
Val (V)   7	  3.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	       902
Hydrogen    H	      1516
Nitrogen    N	       260
Oxygen      O	       284
Sulfur      S	        10

Formula: C902H1516N260O284S10
Total number of atoms: 2972

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.406, assuming all pairs of Cys residues form cystines


Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.406, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 64.87
This classifies the protein as unstable.



Aliphatic index: 92.32

Grand average of hydropathicity (GRAVY): -0.575