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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIRQIILIVS LIGISNAAYQ CKDNNGSNVD WFVFYKLPHL WNHPDNVPIS NGTGFLYFDV

70 80 90 100 110 120
NNKNWKLMPQ GMDVENNAVY YTLQQYYNSN MNTTFSYMYN DEWPDSTIWS NSSGHAKGVT

130 140 150 160 170 180
VFDQYTGFWM IHSIPKFPSK DMFRFPSNAH YYGQMGICIS YNTVSLATIA QQLFYYNTFT

190 200 210 220 230 240
YQFNLPQSFA NQFPVLSQLK NKEYNKSPPL TSTKVLKSLG GQHFRHFAKT GEWGKDLYSD

250 260 270 280 290 300
FVGPTLKSSI KVETWNHQSG DEYNLPSVCD PNHVQSTMSA KYIRLPYAID YSSYEDHSKF

310 320 330 340 350 360
VVAYSESSSK PPIPYVCIGD INRQSHQIHR GGGTMCIYDQ ETYFQFANII SETVPCTKAT

370
AEKATLTVLL IAIITFFK


References and documentation are available.

Number of amino acids: 378 Molecular weight: 43347.93 Theoretical pI: 7.17
Amino acid composition: 
Ala (A) 17 4.5% Arg (R) 6 1.6% Asn (N) 29 7.7% Asp (D) 17 4.5% Cys (C) 6 1.6% Gln (Q) 20 5.3% Glu (E) 11 2.9% Gly (G) 20 5.3% His (H) 12 3.2% Ile (I) 26 6.9% Leu (L) 22 5.8% Lys (K) 22 5.8% Met (M) 10 2.6% Phe (F) 23 6.1% Pro (P) 20 5.3% Ser (S) 36 9.5% Thr (T) 25 6.6% Trp (W) 8 2.1% Tyr (Y) 27 7.1% Val (V) 21 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 28 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 1977 Hydrogen H 2925 Nitrogen N 499 Oxygen O 572 Sulfur S 16 Formula: C1977H2925N499O572S16 Total number of atoms: 5989 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 84605 Abs 0.1% (=1 g/l) 1.952, assuming all pairs of Cys residues form cystines Ext. coefficient 84230 Abs 0.1% (=1 g/l) 1.943, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.24 This classifies the protein as unstable. Aliphatic index: 70.13 Grand average of hydropathicity (GRAVY): -0.348