ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MISGAAAGAL AKTVIAPLDR TKINFQIRND VPFSFRASLR YLQNTYANEG VLALWRGNSA 

        70         80         90        100        110        120 
TMARIVPYAA IQFTAHEQWR RILHVDKDGT NTKGRRFLAG SLAGITSQSL TYPLDLARAR 

       130        140        150        160        170        180 
MAVTDRYTGY RTLRQVFTKI WVEEGPRTLF RGYWATVLGV IPYAGTSFFT YETLKREYYE 

       190        200        210        220        230        240 
VVGNNKPNTL VSLAFGAAAG AAGQTASYPL DIVRRRMQTM RVNTAGGDRY PTILETLVKI 

       250        260        270        280        290 
YREEGVKNGF YKGLSMNWIK GPIAVGISFS TYDLIKAWLT ELANLRRVEK 

References and documentation are available.

Number of amino acids: 290

Molecular weight: 32519.44

Theoretical pI: 10.13

Amino acid composition: 
Ala (A)  32	 11.0%
Arg (R)  26	  9.0%
Asn (N)  13	  4.5%
Asp (D)   9	  3.1%
Cys (C)   0	  0.0%
Gln (Q)   8	  2.8%
Glu (E)  12	  4.1%
Gly (G)  24	  8.3%
His (H)   2	  0.7%
Ile (I)  17	  5.9%
Leu (L)  26	  9.0%
Lys (K)  13	  4.5%
Met (M)   6	  2.1%
Phe (F)  12	  4.1%
Pro (P)  10	  3.4%
Ser (S)  13	  4.5%
Thr (T)  26	  9.0%
Trp (W)   6	  2.1%
Tyr (Y)  16	  5.5%
Val (V)  19	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1472
Hydrogen    H	      2314
Nitrogen    N	       412
Oxygen      O	       409
Sulfur      S	         6

Formula: C1472H2314N412O409S6
Total number of atoms: 4613

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    56840
Abs 0.1% (=1 g/l)   1.748

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 25.10
This classifies the protein as stable.



Aliphatic index: 87.86

Grand average of hydropathicity (GRAVY): -0.151