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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MITGKELRII SLLTLDTVFF LLEITIGYMS HSLALIADSF HMLNDIISLL VALWAVDVAK

70 80 90 100 110 120
NRGPDAKYTY GWKRAEILGA LINAVFLIAL CFSIMIEALQ RLIEPQEIQN PRLVLYVGVA

130 140 150 160 170 180
GLISNVVGLF LFHDHGSDSL HSHSHGSVES GNNDLDIESN ATHSHSHASL PNDNLAIDED

190 200 210 220 230 240
AISSPGPSGQ IGEVLPQSVV NRLSNESQPL LNHDDHDHSH ESKKPGHRSL NMHGVFLHVL

250 260 270 280 290 300
GDALGNIGVI AAALFIWKTE YSWRYYSDPI VSLIITIIIF SSALPLSRRA SRILLQATPS

310 320 330 340 350 360
TISADQIQRE ILAVPGVIAV HDFHVWNLTE SIYIASIHVQ IDCAPDKFMS SAKLIRKIFH

370 380 390 400 410 420
QHGIHSATVQ PEFVSGDVNE DIRRRFSIIA GGSPSSSQEA FDSHGNTEHG RKKRSPTAYG

430 440
ATTASSNCIV DDAVNCNTSN CL


References and documentation are available.

Number of amino acids: 442 Molecular weight: 48344.87 Theoretical pI: 5.88
Amino acid composition: 
Ala (A) 36 8.1% Arg (R) 18 4.1% Asn (N) 22 5.0% Asp (D) 26 5.9% Cys (C) 5 1.1% Gln (Q) 13 2.9% Glu (E) 19 4.3% Gly (G) 27 6.1% His (H) 25 5.7% Ile (I) 45 10.2% Leu (L) 45 10.2% Lys (K) 12 2.7% Met (M) 6 1.4% Phe (F) 16 3.6% Pro (P) 17 3.8% Ser (S) 51 11.5% Thr (T) 17 3.8% Trp (W) 5 1.1% Tyr (Y) 9 2.0% Val (V) 28 6.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 45 Total number of positively charged residues (Arg + Lys): 30 Atomic composition: Carbon C 2155 Hydrogen H 3386 Nitrogen N 598 Oxygen O 645 Sulfur S 11 Formula: C2155H3386N598O645S11 Total number of atoms: 6795 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41160 Abs 0.1% (=1 g/l) 0.851, assuming all pairs of Cys residues form cystines Ext. coefficient 40910 Abs 0.1% (=1 g/l) 0.846, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.40 This classifies the protein as unstable. Aliphatic index: 105.93 Grand average of hydropathicity (GRAVY): 0.068