ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MIVCVAVVGH QNNPLYIQSF TDADDALKLH HIVHCSLDVI EERVNNPKKS GTTLNEAFLG 

        70         80         90        100        110        120 
LLYPTVNYKV YGYLTNTKVK FILVTTDLDV RDTDVRSFFR KFHAAYVDAV SNPFHVPGKK 

       130        140 
ITSRTFAQTV SNIVGSYGLN 

References and documentation are available.

Number of amino acids: 140

Molecular weight: 15678.93

Theoretical pI: 8.54

Amino acid composition: 
Ala (A)   8	  5.7%
Arg (R)   5	  3.6%
Asn (N)  10	  7.1%
Asp (D)   9	  6.4%
Cys (C)   2	  1.4%
Gln (Q)   3	  2.1%
Glu (E)   3	  2.1%
Gly (G)   7	  5.0%
His (H)   6	  4.3%
Ile (I)   7	  5.0%
Leu (L)  12	  8.6%
Lys (K)   9	  6.4%
Met (M)   1	  0.7%
Phe (F)   8	  5.7%
Pro (P)   5	  3.6%
Ser (S)   8	  5.7%
Thr (T)  12	  8.6%
Trp (W)   0	  0.0%
Tyr (Y)   7	  5.0%
Val (V)  18	 12.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 12
Total number of positively charged residues (Arg + Lys): 14

Atomic composition:

Carbon      C	       711
Hydrogen    H	      1107
Nitrogen    N	       189
Oxygen      O	       205
Sulfur      S	         3

Formula: C711H1107N189O205S3
Total number of atoms: 2215

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10555
Abs 0.1% (=1 g/l)   0.673, assuming all pairs of Cys residues form cystines


Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.665, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 19.18
This classifies the protein as stable.



Aliphatic index: 95.93

Grand average of hydropathicity (GRAVY): -0.019