ProtParam
User-provided sequence:
10 20 30 40 50 60
MKALILVGGF GTRLRPLTLS LPKPLVDFAN KPMILHQIEA LKAIGVDEVV LAINYEPEQL
70 80 90 100 110 120
LVMSKFSNDV EATLGIKITC SQETEPLGTA GPLALARDKL VDGSGQPFFV LNSDVISDYP
130 140 150 160 170 180
LEEMIAFHNA HGGEASIMVT KVDEPSKYGV VVMEEATGRV ERFVEKPKLF VGNKINAGIY
190 200 210 220 230 240
LLNPSVLDRI ELRPTSIEKE IFPQIAEAEK LYAMLLPGFW MDIGQPRDYI TGLRLYLDSL
250 260 270 280 290 300
RKKSPSKLAT GPHILGNVLV DETAEIGEGC LIGPNVAIGP GCVVESGVRL SHCTVMRGVH
310 320 330 340 350 360
VKRYACISSS IIGWHSTVGQ WARVENMSIL GKNVYVCDEI YCNGGVVLHN KEIKSDILKP
DIVM
References and
documentation are available.
Number of amino acids: 364
Molecular weight: 39808.44
Theoretical pI: 5.70
Total number of negatively charged residues (Asp + Glu): 43
Total number of positively charged residues (Arg + Lys): 36
Atomic composition:
Carbon C 1789
Hydrogen H 2878
Nitrogen N 468
Oxygen O 518
Sulfur S 18
Formula: C
1789H
2878N
468O
518S
18
Total number of atoms: 5671
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 31775
Abs 0.1% (=1 g/l) 0.798, assuming all pairs of Cys residues form cystines
Ext. coefficient 31400
Abs 0.1% (=1 g/l) 0.789, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 37.70
This classifies the protein as stable.
Aliphatic index: 107.86
Grand average of hydropathicity (GRAVY): 0.133