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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKCRVWSEAR VYTNINKQRT EEYWDYENTV IDWSTNTKDY EIENKVGRGK YSEVFQGVKL

70 80 90 100 110 120
DSKVKIVIKM LKPVKKKKIK REIKILTDLS NEKVPPTTLP FQKDQYYTNQ KEDVLKFIRP

130 140 150 160 170 180
YIFDQPHNGH ANIIHLFDII KDPISKTPAL VFEYVDNVDF RILYPKLTDL EIRFYMFELL

190 200 210 220 230 240
KALDYCHSMG IMHRDVKPHN VMIDHKNKKL RLIDWGLAEF YHVNMEYNVR VASRFFKGPE

250 260 270 280 290 300
LLVDYRMYDY SLDLWSFGTM LASMIFKREP FFHGTSNTDQ LVKIVKVLGT SDFEKYLLKY

310 320 330 340 350 360
EITLPREFYD MDQYIRKPWH RFINDGNKHL SGNDEIIDLI DNLLRYDHQE RLTAKEAMGH

370
PWFAPIREQI EK


References and documentation are available.

Number of amino acids: 372 Molecular weight: 44667.58 Theoretical pI: 8.63
Amino acid composition: 
Ala (A) 10 2.7% Arg (R) 20 5.4% Asn (N) 19 5.1% Asp (D) 29 7.8% Cys (C) 2 0.5% Gln (Q) 10 2.7% Glu (E) 25 6.7% Gly (G) 13 3.5% His (H) 13 3.5% Ile (I) 30 8.1% Leu (L) 32 8.6% Lys (K) 38 10.2% Met (M) 12 3.2% Phe (F) 20 5.4% Pro (P) 16 4.3% Ser (S) 14 3.8% Thr (T) 17 4.6% Trp (W) 7 1.9% Tyr (Y) 22 5.9% Val (V) 23 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 54 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2047 Hydrogen H 3148 Nitrogen N 532 Oxygen O 563 Sulfur S 14 Formula: C2047H3148N532O563S14 Total number of atoms: 6304 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 71405 Abs 0.1% (=1 g/l) 1.599, assuming all pairs of Cys residues form cystines Ext. coefficient 71280 Abs 0.1% (=1 g/l) 1.596, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.14 This classifies the protein as stable. Aliphatic index: 85.62 Grand average of hydropathicity (GRAVY): -0.549