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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKDDGAPNVA KTTDPPPPKR FPSGRAHSPH GDGEAGKLLH GSVFSKRFFG SFQWEEFACG

70 80 90 100 110 120
CGAAFVNIAV TYPIYKMIFR QMLHGVPITS AFAQLRHEGL GFLYRGMLPP LAQKTISLSI

130 140 150 160 170 180
MFGVFDGTRR YLVEDYRLND YGAKVLAAVV AGSAESILLP FERVQTLLAD SKFHQHFSNT

190 200 210 220 230 240
QNAFRYVVSH HGYRELYRGL EPVFWRNGLS NALFFVLREE ASVRLPKRKS VSTRTVQEFI

250 260 270 280 290 300
AGAVIGASIS TIFYPLNVIK VSLQSEMGQR SEGSWQACKR IYVERDRRIG NFYRGCPFNT

310 320 330
GRSFISWGIM NTAYENLKKL MQQQPPLPLA SE


References and documentation are available.

Number of amino acids: 332 Molecular weight: 37362.95 Theoretical pI: 9.71
Amino acid composition: 
Ala (A) 26 7.8% Arg (R) 25 7.5% Asn (N) 12 3.6% Asp (D) 9 2.7% Cys (C) 4 1.2% Gln (Q) 14 4.2% Glu (E) 17 5.1% Gly (G) 28 8.4% His (H) 9 2.7% Ile (I) 16 4.8% Leu (L) 28 8.4% Lys (K) 15 4.5% Met (M) 8 2.4% Phe (F) 24 7.2% Pro (P) 19 5.7% Ser (S) 26 7.8% Thr (T) 13 3.9% Trp (W) 4 1.2% Tyr (Y) 13 3.9% Val (V) 22 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 26 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 1695 Hydrogen H 2608 Nitrogen N 470 Oxygen O 463 Sulfur S 12 Formula: C1695H2608N470O463S12 Total number of atoms: 5248 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41620 Abs 0.1% (=1 g/l) 1.114, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 1.107, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.31 This classifies the protein as stable. Aliphatic index: 78.73 Grand average of hydropathicity (GRAVY): -0.192