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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKDSMSILTQ TPSEPNAAHP QLHHHLSTLQ QQHHQHHLHY GLQPPAVAHS IHSTTTMSSG

70 80 90 100 110 120
GSTTTASGIG KPNRSRFMIN DILAGSAAAA FYKQQQHHQQ LHHHNNNNNS GSSGGSSPAH

130 140 150 160 170 180
SNNNNNINGD NCEASNVAGV GVLPSALHHP QPHPPTHPHT HPHALMHPHG KLGHFPPTAG

190 200 210 220 230 240
GNGLNVAQYA AAMQQHYAAA AAAAAARNNA AAAAAAAAAA AAAGVAAPPV DGGVDGGVGL

250 260 270 280 290 300
APPAGGDLDD SSDYHEENED CDSGNMDDHS VCSNGGKDDD GNSVKSGSTS DMSGLSKKQR

310 320 330 340 350 360
KARTAFTDHQ LQTLEKSFER QKYLSVQERQ ELAHKLDLSD CQVKTWYQNR RTKWKRQTAV

370 380 390 400 410 420
GLELLAEAGN FAAFQRLYGG SPYLGAWPYA AAAGAAHGAT PHTNIDIYYR QAAAAAAMQK

430 440 450 460 470 480
PLPYNLYAGV PSVGVGVGVG VGPAPFSHLS ASSSLSSLSS YYQSAAAAAS AANPGGPHPV

490 500 510 520 530 540
APPPSVGGGS PPSGLVKPIP AHSASASPPP RPPSTPSPTL NPGSPPGRSV DSCSQSDDED


QIQV


References and documentation are available.

Number of amino acids: 544 Molecular weight: 56083.41 Theoretical pI: 6.67
Amino acid composition: 
Ala (A) 83 15.3% Arg (R) 14 2.6% Asn (N) 30 5.5% Asp (D) 25 4.6% Cys (C) 5 0.9% Gln (Q) 32 5.9% Glu (E) 12 2.2% Gly (G) 52 9.6% His (H) 37 6.8% Ile (I) 10 1.8% Leu (L) 34 6.2% Lys (K) 17 3.1% Met (M) 9 1.7% Phe (F) 8 1.5% Pro (P) 49 9.0% Ser (S) 60 11.0% Thr (T) 23 4.2% Trp (W) 3 0.6% Tyr (Y) 16 2.9% Val (V) 25 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 37 Total number of positively charged residues (Arg + Lys): 31 Atomic composition: Carbon C 2416 Hydrogen H 3714 Nitrogen N 742 Oxygen O 780 Sulfur S 14 Formula: C2416H3714N742O780S14 Total number of atoms: 7666 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 40590 Abs 0.1% (=1 g/l) 0.724, assuming all pairs of Cys residues form cystines Ext. coefficient 40340 Abs 0.1% (=1 g/l) 0.719, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.38 This classifies the protein as unstable. Aliphatic index: 60.13 Grand average of hydropathicity (GRAVY): -0.552