Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKEIAMRNSK RKPEPTPFAG KKLRSTRLRR KRAQISPVLV QSPLWSKQIG VSAASVDSCS

70 80 90 100 110 120
DLLADDNVSC GSSRVEKSSN PKKTLIEEVE VSKPGYNVKE TIGDSKFRRI TRSYSKLHKE

130 140 150 160 170 180
KEGDEIEVSE SSCVDSNSGA GLRRLNVKGN KINDNDEISF SRSDVTFAGH VSNSRSLNFE

190 200 210 220 230 240
SENKESDVVS VISGVEYCSK FGSVTGGADN EEIEISKPSS FVEADSSLGS AKELKPELEI

250 260 270 280 290 300
VGCVSDLACS EKFSEEVSDS LDDESSEQRS EIYSQYSDFD YSDYTPSIFF DSGSEFSEKS

310 320 330 340 350 360
SSDSPISHSR SLYLQFKEQF CRSTIPNDFG SSCEEEIHSE LLRFDDEEVE ESYLRLRERE

370 380 390 400 410 420
RSHAYMRDCA KAYCSRMDNT GLIPRLRSIM VQWIVKQCSD MGLQQETLFL GVGLLDRFLS

430 440 450 460 470 480
KGSFKSERTL ILVGIASLTL ATRIEENQPY NSIRKRNFTI QNLRYSRHEV VAMEWLVQEV

490 500 510 520 530 540
LNFKCFTPTI FNFLWFYLKA ARANPEVERK AKSLAVTSLS DQTQLCFWPS TVAAALVVLA

550 560 570
CIEHNKISAY QRVIKVHVRT TDNELPECVK SLDWLLGQ


References and documentation are available.

Number of amino acids: 578 Molecular weight: 65201.21 Theoretical pI: 5.54
Amino acid composition: 
Ala (A) 28 4.8% Arg (R) 38 6.6% Asn (N) 24 4.2% Asp (D) 32 5.5% Cys (C) 15 2.6% Gln (Q) 18 3.1% Glu (E) 55 9.5% Gly (G) 25 4.3% His (H) 8 1.4% Ile (I) 30 5.2% Leu (L) 48 8.3% Lys (K) 38 6.6% Met (M) 7 1.2% Phe (F) 26 4.5% Pro (P) 18 3.1% Ser (S) 84 14.5% Thr (T) 22 3.8% Trp (W) 6 1.0% Tyr (Y) 15 2.6% Val (V) 41 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 87 Total number of positively charged residues (Arg + Lys): 76 Atomic composition: Carbon C 2845 Hydrogen H 4512 Nitrogen N 794 Oxygen O 916 Sulfur S 22 Formula: C2845H4512N794O916S22 Total number of atoms: 9089 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 56225 Abs 0.1% (=1 g/l) 0.862, assuming all pairs of Cys residues form cystines Ext. coefficient 55350 Abs 0.1% (=1 g/l) 0.849, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.56 This classifies the protein as unstable. Aliphatic index: 78.04 Grand average of hydropathicity (GRAVY): -0.483