ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKFQVVLSAL LACSSAVVAS PIENLFKYRA VKASHSKNIN STLPAWNGSN SSNVTYANGT 

        70         80         90        100        110        120 
NSTTNTTTAE SSQLQIIVTG GQVPITNSSL THTNYTRLFN SSSALNITEL YNVARVVNET 

       130        140        150        160        170        180 
IQDKSSAGAV VVANAKSLEA VSFFFSIIFD TEKPIVVTED SAYAIPVANN KNATKRGVLS 

       190        200        210        220        230        240 
VTSDKLVYSG VFTPPTACSY GAGLPVAIVD DQDEVKWFFD ASKPTLISSD SIIRKEYSNF 

       250        260        270        280        290        300 
TTPYGLLENG VPIVPIVYDG GYSSSLIDSL SSAVQGLVVV SSGSTNSTSS TIESTEIPVV 

       310        320        330        340        350 
YAQANTPLNF IDNKDVPKNA VGAGYLSPIK AQILLSIAAV NGVTSKSALE SIFP 

References and documentation are available.

Number of amino acids: 354

Molecular weight: 37327.98

Theoretical pI: 5.29

Amino acid composition: 
Ala (A)  33	  9.3%
Arg (R)   5	  1.4%
Asn (N)  27	  7.6%
Asp (D)  13	  3.7%
Cys (C)   2	  0.6%
Gln (Q)   9	  2.5%
Glu (E)  13	  3.7%
Gly (G)  18	  5.1%
His (H)   2	  0.6%
Ile (I)  25	  7.1%
Leu (L)  25	  7.1%
Lys (K)  17	  4.8%
Met (M)   1	  0.3%
Phe (F)  13	  3.7%
Pro (P)  17	  4.8%
Ser (S)  51	 14.4%
Thr (T)  30	  8.5%
Trp (W)   2	  0.6%
Tyr (Y)  13	  3.7%
Val (V)  38	 10.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	      1664
Hydrogen    H	      2638
Nitrogen    N	       428
Oxygen      O	       537
Sulfur      S	         3

Formula: C1664H2638N428O537S3
Total number of atoms: 5270

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30495
Abs 0.1% (=1 g/l)   0.817, assuming all pairs of Cys residues form cystines


Ext. coefficient    30370
Abs 0.1% (=1 g/l)   0.814, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.64
This classifies the protein as stable.



Aliphatic index: 95.54

Grand average of hydropathicity (GRAVY): 0.121