ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKGGESKAEA TSTDQRLKTR GRKAGKKTKK DPNQPKRPPS AFFVFLEDFR KEFNLANPNN 

        70         80         90        100        110        120 
KSVATVGKAA GARWKAMTDE DKAPYVAKAE SRKTEYIKNV QQYNLKLASG TNREEDDSDK 

       130 
SKSEVDEAVS EEEAEDDD 

References and documentation are available.

Number of amino acids: 138

Molecular weight: 15419.99

Theoretical pI: 7.80

Amino acid composition: 
Ala (A)  16	 11.6%
Arg (R)   8	  5.8%
Asn (N)   8	  5.8%
Asp (D)  12	  8.7%
Cys (C)   0	  0.0%
Gln (Q)   4	  2.9%
Glu (E)  15	 10.9%
Gly (G)   7	  5.1%
His (H)   0	  0.0%
Ile (I)   1	  0.7%
Leu (L)   5	  3.6%
Lys (K)  20	 14.5%
Met (M)   2	  1.4%
Phe (F)   5	  3.6%
Pro (P)   6	  4.3%
Ser (S)  10	  7.2%
Thr (T)   8	  5.8%
Trp (W)   1	  0.7%
Tyr (Y)   3	  2.2%
Val (V)   7	  5.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 27
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	       661
Hydrogen    H	      1061
Nitrogen    N	       195
Oxygen      O	       226
Sulfur      S	         2

Formula: C661H1061N195O226S2
Total number of atoms: 2145

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     9970
Abs 0.1% (=1 g/l)   0.647

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.08
This classifies the protein as stable.



Aliphatic index: 43.26

Grand average of hydropathicity (GRAVY): -1.317