ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKHYVLVHGG CHGAWCWYKV KPVLEASGHR VTVVDLTASG VNMSKVEEIQ TLADYAKPLL 

        70         80         90        100        110        120 
EVLESFGSED KVILVAHSLG GISVGLAADM FPSKISVAVF ITSFMPDTTN PHLFMFSKSV 

       130        140        150 
LSQEDVSTFS SRRISSSKLQ LSTTMIGKDV SSG 

References and documentation are available.

Number of amino acids: 153

Molecular weight: 16538.08

Theoretical pI: 6.58

Amino acid composition: 
Ala (A)   9	  5.9%
Arg (R)   3	  2.0%
Asn (N)   2	  1.3%
Asp (D)   7	  4.6%
Cys (C)   2	  1.3%
Gln (Q)   3	  2.0%
Glu (E)   7	  4.6%
Gly (G)  11	  7.2%
His (H)   6	  3.9%
Ile (I)   7	  4.6%
Leu (L)  14	  9.2%
Lys (K)  10	  6.5%
Met (M)   6	  3.9%
Phe (F)   7	  4.6%
Pro (P)   5	  3.3%
Ser (S)  22	 14.4%
Thr (T)   9	  5.9%
Trp (W)   2	  1.3%
Tyr (Y)   3	  2.0%
Val (V)  18	 11.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 13

Atomic composition:

Carbon      C	       740
Hydrogen    H	      1173
Nitrogen    N	       191
Oxygen      O	       221
Sulfur      S	         8

Formula: C740H1173N191O221S8
Total number of atoms: 2333

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15595
Abs 0.1% (=1 g/l)   0.943, assuming all pairs of Cys residues form cystines


Ext. coefficient    15470
Abs 0.1% (=1 g/l)   0.935, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.42
This classifies the protein as unstable.



Aliphatic index: 93.53

Grand average of hydropathicity (GRAVY): 0.211