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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKIQTNAVNV LQRTSAYLKS GLLKETPAWY NVVASIPPST KFTREPRFKN PSNGHIIGKL

70 80 90 100 110 120
VDVTEQPHAN NKGLYKTRPN SSDKRVGVKR LYRPPKLTYV EDRLRSLFYK QHPWELSRPK

130 140 150 160 170 180
ILVENEIGDE NYDWSHMLQI GRPLDGESVI QRTMYLIKTK QYGDMVEAYD HARYEFYALR

190 200 210 220 230 240
MQEETEQQVA LEEAEMFGSL FGVSAIEHGI QKEQEVLDVW EKKVVEETEL MAARTSNPAG

250 260
SWKDDTTLNT AQEEESTTSE NLHF


References and documentation are available.

Number of amino acids: 264 Molecular weight: 30513.38 Theoretical pI: 5.88
Amino acid composition: 
Ala (A) 15 5.7% Arg (R) 15 5.7% Asn (N) 13 4.9% Asp (D) 11 4.2% Cys (C) 0 0.0% Gln (Q) 13 4.9% Glu (E) 28 10.6% Gly (G) 13 4.9% His (H) 7 2.7% Ile (I) 11 4.2% Leu (L) 22 8.3% Lys (K) 19 7.2% Met (M) 7 2.7% Phe (F) 7 2.7% Pro (P) 13 4.9% Ser (S) 17 6.4% Thr (T) 18 6.8% Trp (W) 5 1.9% Tyr (Y) 12 4.5% Val (V) 18 6.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 34 Atomic composition: Carbon C 1355 Hydrogen H 2117 Nitrogen N 373 Oxygen O 416 Sulfur S 7 Formula: C1355H2117N373O416S7 Total number of atoms: 4268 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 45380 Abs 0.1% (=1 g/l) 1.487 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.99 This classifies the protein as unstable. Aliphatic index: 74.20 Grand average of hydropathicity (GRAVY): -0.739