ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKISLHNKRQ RGDQNQNMSV FNVLKPLLKG SNSFKVKLNG FLFNNVSTIT IRTLMKTHKG 

        70         80         90        100        110 
TAKRWRRTGN TFKRGIAGRK HGNIGWSHRS LKALTGRKIA HPAYSKHLKR LLPYH 

References and documentation are available.

Number of amino acids: 115

Molecular weight: 13243.56

Theoretical pI: 12.26

Amino acid composition: 
Ala (A)   5	  4.3%
Arg (R)  11	  9.6%
Asn (N)  10	  8.7%
Asp (D)   1	  0.9%
Cys (C)   0	  0.0%
Gln (Q)   3	  2.6%
Glu (E)   0	  0.0%
Gly (G)  10	  8.7%
His (H)   7	  6.1%
Ile (I)   6	  5.2%
Leu (L)  12	 10.4%
Lys (K)  15	 13.0%
Met (M)   3	  2.6%
Phe (F)   5	  4.3%
Pro (P)   3	  2.6%
Ser (S)   8	  7.0%
Thr (T)   8	  7.0%
Trp (W)   2	  1.7%
Tyr (Y)   2	  1.7%
Val (V)   4	  3.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 1
Total number of positively charged residues (Arg + Lys): 26

Atomic composition:

Carbon      C	       591
Hydrogen    H	       968
Nitrogen    N	       192
Oxygen      O	       149
Sulfur      S	         3

Formula: C591H968N192O149S3
Total number of atoms: 1903

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    13980
Abs 0.1% (=1 g/l)   1.056

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.70
This classifies the protein as stable.



Aliphatic index: 75.48

Grand average of hydropathicity (GRAVY): -0.752