ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKITCTDLVY VFILLFLNTS CVQAVFSDDA FITDWQLANL GPWEKVIPDS RDRNRVLILS 

        70         80         90        100        110        120 
NPTETSCLVS SFNVSSGQIL FRNVLPFTID EIQLDSNDHN AMVCVNSSSN HWQKYDLHDW 

       130        140        150        160        170        180 
FLLEEGVDNA PSTTILPQSS YLNDQVSIKN NELHILDEQS KLAEWKLELP QGFNKVEYFH 

       190        200        210        220        230        240 
REDPLALVLN VNDTQYMGFS ANGTELIPVW QRDEWLTNVV DYAVLDVFDS RDVELNKDMK 

       250        260        270        280        290        300 
AELDSNSLWN AYWLRLTTNW NRLINLLKEN QFSPGRVFTK LLALDAKDTT VSDLKFGFAK 

       310        320        330        340        350        360 
ILIVLTHDGF IGGLDMVNKG QLIWKLDLEI DQGVKMFWTD KNHDELVVFS HDGHYLTIEV 

       370        380        390        400        410        420 
TKDQPIIKSR SPLSERKTVD SVIRLNEHDH QYLIKFEDKD HLLFKLNPGK NTDVPIVANN 

       430        440        450        460        470        480 
HSSSHIFVTE HDTNGIYGYI IENDTVKQTW KKAVNSKEKM VAYSKRETTN LNTLGITLGD 

       490        500        510        520        530        540 
KSVLYKYLYP NLAAYLIANE EHHTITFNLI DTITGEILIT QEHKDSPDFR FPMDIVFGEY 

       550        560        570        580        590        600 
WVVYSYFSSE PVPEQKLVVV ELYESLTPDE RLSNSSDNFS YDPLTGHINK PQFQTKQFIF 

       610        620        630        640        650        660 
PEIIKTMSIS KTTDDITTKA IVMELENGQI TYIPKLLLNA RGKPAEEMAK DKKKEFMATP 

       670        680        690        700        710        720 
YTPVIPINDN FIITHFRNLL PGSDSQLISI PTNLESTSII CDLGLDVFCT RITPSGQFDL 

       730        740        750        760 
MSPTFEKGKL LITIFVLLVI TYFIRPSVSN KKLKSQWLIK 

References and documentation are available.

Number of amino acids: 760

Molecular weight: 87181.39

Theoretical pI: 5.15

Amino acid composition: 
Ala (A)  25	  3.3%
Arg (R)  20	  2.6%
Asn (N)  51	  6.7%
Asp (D)  57	  7.5%
Cys (C)   6	  0.8%
Gln (Q)  26	  3.4%
Glu (E)  44	  5.8%
Gly (G)  28	  3.7%
His (H)  20	  2.6%
Ile (I)  59	  7.8%
Leu (L)  85	 11.2%
Lys (K)  52	  6.8%
Met (M)  13	  1.7%
Phe (F)  39	  5.1%
Pro (P)  33	  4.3%
Ser (S)  56	  7.4%
Thr (T)  55	  7.2%
Trp (W)  15	  2.0%
Tyr (Y)  24	  3.2%
Val (V)  52	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 101
Total number of positively charged residues (Arg + Lys): 72

Atomic composition:

Carbon      C	      3957
Hydrogen    H	      6134
Nitrogen    N	      1004
Oxygen      O	      1175
Sulfur      S	        19

Formula: C3957H6134N1004O1175S19
Total number of atoms: 12289

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   118635
Abs 0.1% (=1 g/l)   1.361, assuming all pairs of Cys residues form cystines


Ext. coefficient   118260
Abs 0.1% (=1 g/l)   1.356, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.41
This classifies the protein as stable.



Aliphatic index: 97.03

Grand average of hydropathicity (GRAVY): -0.225