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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKITKYRTKK SLGQCFILDP AIAEKIVSYA GCLEQYNVIE VGPGLGIMTQ SILNKEVRRL

70 80 90 100 110 120
TAIEKDRRLS NIHSKLKEAH AEYDCIFEDI LDVNIEQLLS QSPLKMISNL PYNISVILLL

130 140 150 160 170 180
KLLPYIHRFE KLILMFQKEV ADRIVAQPNT KSYSILSILV QLLCDVRKVE DFPPEIFSPS

190 200 210 220 230 240
PKVYSSVIEI TPLLSPRFSV DNSYFAQVLK KLFHCRRKTI RNSLKSCIKD ADALFIGCNI

250 260
DPNARAESLT IEQLCSLTNA LKARNINII


References and documentation are available.

Number of amino acids: 269 Molecular weight: 30615.04 Theoretical pI: 9.02
Amino acid composition: 
Ala (A) 15 5.6% Arg (R) 14 5.2% Asn (N) 14 5.2% Asp (D) 12 4.5% Cys (C) 8 3.0% Gln (Q) 10 3.7% Glu (E) 16 5.9% Gly (G) 6 2.2% His (H) 4 1.5% Ile (I) 31 11.5% Leu (L) 34 12.6% Lys (K) 22 8.2% Met (M) 4 1.5% Phe (F) 10 3.7% Pro (P) 13 4.8% Ser (S) 23 8.6% Thr (T) 9 3.3% Trp (W) 0 0.0% Tyr (Y) 9 3.3% Val (V) 15 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 28 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1381 Hydrogen H 2257 Nitrogen N 365 Oxygen O 391 Sulfur S 12 Formula: C1381H2257N365O391S12 Total number of atoms: 4406 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 13910 Abs 0.1% (=1 g/l) 0.454, assuming all pairs of Cys residues form cystines Ext. coefficient 13410 Abs 0.1% (=1 g/l) 0.438, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 58.65 This classifies the protein as unstable. Aliphatic index: 115.99 Grand average of hydropathicity (GRAVY): 0.041