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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKKGAKRKGV SKAGRKAAVA ETQNDEVIEE TTKTTQEESQ QHEEEVVDEV KENGEEEEAK

70 80 90 100 110 120
GDQEEEEDAK PDSLEEDEEN QEDEVKAEEV KEEVEKKPVA RRGGKRKRAT KKDTEIKDEK

130 140 150 160 170 180
KPVPKAKKPR AAKVKEEPVY FEEKRSLEDL WKVAFPVGTE WDQLDALYEF NWDFQNLEEA

190 200 210 220 230 240
LEEGGKLYGK KVYVFGCTEP QLVPYKGANK IVHVPAVVVI ESPFPPSDKI GITSVQREVE

250 260 270 280 290 300
EIIPMKKMKM DWLPYIPIEK RDRQVDKMNS QIFTLGCTQR RSALRHMKED QLKKFEYCLP

310 320 330 340 350 360
YFYQPFKEDE LEQSTEVQIM FPSEPPVVCE FDWEFDELQE FVDKLVEEEA LPAEQADEFK

370 380 390 400 410 420
EYVKEQVRAA KKANREAKDA RKKAIEEMSE DTKQAFQKMK FYKFYPQPSP DTPDVSGVQS

430
PFINRYYGKA HEVL


References and documentation are available.

Number of amino acids: 434 Molecular weight: 50516.84 Theoretical pI: 4.92
Amino acid composition: 
Ala (A) 30 6.9% Arg (R) 18 4.1% Asn (N) 9 2.1% Asp (D) 27 6.2% Cys (C) 4 0.9% Gln (Q) 24 5.5% Glu (E) 72 16.6% Gly (G) 17 3.9% His (H) 4 0.9% Ile (I) 14 3.2% Leu (L) 19 4.4% Lys (K) 56 12.9% Met (M) 9 2.1% Phe (F) 19 4.4% Pro (P) 27 6.2% Ser (S) 15 3.5% Thr (T) 15 3.5% Trp (W) 5 1.2% Tyr (Y) 14 3.2% Val (V) 36 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 99 Total number of positively charged residues (Arg + Lys): 74 Atomic composition: Carbon C 2243 Hydrogen H 3508 Nitrogen N 590 Oxygen O 710 Sulfur S 13 Formula: C2243H3508N590O710S13 Total number of atoms: 7064 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 48610 Abs 0.1% (=1 g/l) 0.962, assuming all pairs of Cys residues form cystines Ext. coefficient 48360 Abs 0.1% (=1 g/l) 0.957, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 70.09 This classifies the protein as unstable. Aliphatic index: 60.62 Grand average of hydropathicity (GRAVY): -1.034