ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKKLFKKKKG VSPHMYMLPE ESNSNTATNA PSYSVGGTTA NSYSSNSYND NNNSNSTYGS 

        70         80         90        100        110        120 
SNNYGNYGSS NNYGSYGASN TYGSNGSSNN YGNYGATNSN GDAGYSITPI RNDPYARKDM 

       130        140        150        160        170        180 
PPMKSSAAVT ERPSMHRSAP SQDTLDLKKQ ELFAGARIQN DDESTTDTIP HNDDGTEGDE 

       190        200        210        220        230        240 
YGEGYRDGYE EDQEVEAIKQ KIQFVKQDSL SSTRNALLMA GNAEQMGLAT LANLGEQTEK 

       250        260        270        280        290        300 
IATAEKELDI SKIHAKRAEE QARELKTLNR SMFAIHVPKP WGKAKRVAAE EARLAAKRDA 

       310        320        330        340        350        360 
ERQDEMLNRQ FAYRSQKRID QAMKDNMKSN KKKGDSKGVS ILERSHYQFE PDAEDDAMEK 

       370        380        390        400        410 
EIDGNLDQIG ALATRLKGLA YATGQEIDSQ NARLGSIHDK SDRLDTDVYL NVERLRHIH 

References and documentation are available.

Number of amino acids: 419

Molecular weight: 46430.77

Theoretical pI: 5.83

Amino acid composition: 
Ala (A)  40	  9.5%
Arg (R)  23	  5.5%
Asn (N)  35	  8.4%
Asp (D)  31	  7.4%
Cys (C)   0	  0.0%
Gln (Q)  18	  4.3%
Glu (E)  31	  7.4%
Gly (G)  31	  7.4%
His (H)   9	  2.1%
Ile (I)  17	  4.1%
Leu (L)  25	  6.0%
Lys (K)  32	  7.6%
Met (M)  13	  3.1%
Phe (F)   6	  1.4%
Pro (P)  13	  3.1%
Ser (S)  41	  9.8%
Thr (T)  22	  5.3%
Trp (W)   1	  0.2%
Tyr (Y)  21	  5.0%
Val (V)  10	  2.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 62
Total number of positively charged residues (Arg + Lys): 55

Atomic composition:

Carbon      C	      1972
Hydrogen    H	      3116
Nitrogen    N	       592
Oxygen      O	       681
Sulfur      S	        13

Formula: C1972H3116N592O681S13
Total number of atoms: 6374

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    36790
Abs 0.1% (=1 g/l)   0.792

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.57
This classifies the protein as unstable.



Aliphatic index: 55.56

Grand average of hydropathicity (GRAVY): -1.055