ProtParam
User-provided sequence:
10 20 30 40 50 60
MKKVVAVVKL QLPAGKATPA PPVGPALGQH GANIMEFVKA FNAATANMGD AIVPVEITIY
70 80 90 100 110 120
ADRSFTFVTK TPPASYLIRK AAGLEKGAHK PGREKVGRIT WEQVLEIAKQ KMPDLNTTDL
130 140
EAAARMIAGS ARSMGVEVVG APEVKDA
References and
documentation are available.
Number of amino acids: 147
Molecular weight: 15505.13
Theoretical pI: 9.56
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 692
Hydrogen H 1133
Nitrogen N 191
Oxygen O 199
Sulfur S 6
Formula: C
692H
1133N
191O
199S
6
Total number of atoms: 2221
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.547
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 39.22
This classifies the protein as stable.
Aliphatic index: 88.37
Grand average of hydropathicity (GRAVY): -0.009