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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKLGSKQVKI ISLLLLDTVF FGIEITTGYL SHSLALIADS FHMLNDIISL VVALWAVNVA

70 80 90 100 110 120
KNRNPDSTYT YGWKRAEILG ALINAVFLIA LCVSILIEAL QRIIAPPVIE NPKFVLYVGV

130 140 150 160 170 180
AGLISNTVGL FLFHDNDQEH GHGHGHSHGG IFADHEMHMP SSHTHTHAHV DGIENTTPMD

190 200 210 220 230 240
STDNISEIMP NAIVDSFMNE NTRLLTPENA SKTPSYSTSS HTIASGGNYT EHNKRKRSLN

250 260 270 280 290 300
MHGVFLHVLG DALGNIGVML SAFFIWKTDY SWKYYTDPLV SLIITGIIFS SALPLSCKAS

310 320 330 340 350 360
KILLQATPST LSGDQVEGDL LKIPGIIAIH DFHIWNLTES IFIASLHIQL DISPEQFTDL

370 380 390 400 410 420
AKIVRSKLHR YGIHSATLQP EFITREVTST ERAGDSQGDH LQNDPLSLRP KTYGTGISGS

430
TCLIDDAANC NTADCLEDH


References and documentation are available.

Number of amino acids: 439 Molecular weight: 48154.87 Theoretical pI: 5.81
Amino acid composition: 
Ala (A) 30 6.8% Arg (R) 11 2.5% Asn (N) 22 5.0% Asp (D) 26 5.9% Cys (C) 5 1.1% Gln (Q) 10 2.3% Glu (E) 18 4.1% Gly (G) 30 6.8% His (H) 25 5.7% Ile (I) 43 9.8% Leu (L) 48 10.9% Lys (K) 17 3.9% Met (M) 9 2.1% Phe (F) 17 3.9% Pro (P) 17 3.9% Ser (S) 41 9.3% Thr (T) 32 7.3% Trp (W) 5 1.1% Tyr (Y) 11 2.5% Val (V) 22 5.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 44 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 2159 Hydrogen H 3376 Nitrogen N 576 Oxygen O 644 Sulfur S 14 Formula: C2159H3376N576O644S14 Total number of atoms: 6769 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44140 Abs 0.1% (=1 g/l) 0.917, assuming all pairs of Cys residues form cystines Ext. coefficient 43890 Abs 0.1% (=1 g/l) 0.911, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.45 This classifies the protein as stable. Aliphatic index: 102.21 Grand average of hydropathicity (GRAVY): 0.056