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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKLPIYLDYS ATTPVDPRVA EKMMQFLTLD GTFGNPASRS HRFGWQAEEA VDIARNQIAE

70 80 90 100 110 120
LVGADPREIV FTSGATESDN LAIKGAANFY QKKGKHIITS KTEHKAVLDT CRQLEREGFE

130 140 150 160 170 180
VTYLAPQRNG IIDLNELEAA MRDDTILVSI MHVNNEIGVV QDIATIGEMC RARGIIYHVD

190 200 210 220 230 240
ATQSVGKLPI DLSQLKVDLM SFSGHKIYGP KGIGALYVRR KPRIRIEAQM HGGGHERGMR

250 260 270 280 290 300
SGTLPVHQIV GMGEAYRIAK EEMETEMARL RGLRNRLWNG IKDIEEVYLN GDLEQGAPNI

310 320 330 340 350 360
LNVSFNYVEG ESLIMALKDL AVSSGSACTS ATLEPSYVLR ALGMNDELAH SSIRFSLGRF

370 380 390 400
TTEEEIDYTI DLVRKSIGRL RDLSPLWEMY KQGVDLNSIE WAHH


References and documentation are available.

Number of amino acids: 404 Molecular weight: 45106.47 Theoretical pI: 5.80
Amino acid composition: 
Ala (A) 32 7.9% Arg (R) 28 6.9% Asn (N) 16 4.0% Asp (D) 22 5.4% Cys (C) 3 0.7% Gln (Q) 13 3.2% Glu (E) 33 8.2% Gly (G) 34 8.4% His (H) 12 3.0% Ile (I) 32 7.9% Leu (L) 37 9.2% Lys (K) 18 4.5% Met (M) 15 3.7% Phe (F) 10 2.5% Pro (P) 13 3.2% Ser (S) 25 6.2% Thr (T) 20 5.0% Trp (W) 4 1.0% Tyr (Y) 13 3.2% Val (V) 24 5.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 1983 Hydrogen H 3169 Nitrogen N 563 Oxygen O 602 Sulfur S 18 Formula: C1983H3169N563O602S18 Total number of atoms: 6335 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41495 Abs 0.1% (=1 g/l) 0.920, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 0.917, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.61 This classifies the protein as stable. Aliphatic index: 91.76 Grand average of hydropathicity (GRAVY): -0.274