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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKLYFIALQF LTVVPLPFRL RWDERALGRS MAFFPLAGLT LGTLLAGADM LFAALVPRPV

70 80 90 100 110 120
SDLLLVALLA GVTGALHLDG LADVCDGLAA RGGRERFLAV MKDPRVGAVG VVGLVLGLAL

130 140 150 160 170 180
KYQALLAVPD DLKRQALLLF PAVARYAQVQ MTVGANRARQ DGLGAAFIAG TGMFQLVTAG

190 200 210 220 230 240
TITAVAAWLL LGPAGMAVLA ASVLFTGGFR WWFHRHLGGV TGDVIGCASE LNEILCLLVI


LALHRG


References and documentation are available.

Number of amino acids: 246 Molecular weight: 25927.93 Theoretical pI: 9.50
Amino acid composition: 
Ala (A) 38 15.4% Arg (R) 16 6.5% Asn (N) 2 0.8% Asp (D) 11 4.5% Cys (C) 3 1.2% Gln (Q) 7 2.8% Glu (E) 4 1.6% Gly (G) 29 11.8% His (H) 4 1.6% Ile (I) 6 2.4% Leu (L) 47 19.1% Lys (K) 4 1.6% Met (M) 7 2.8% Phe (F) 13 5.3% Pro (P) 9 3.7% Ser (S) 4 1.6% Thr (T) 11 4.5% Trp (W) 4 1.6% Tyr (Y) 3 1.2% Val (V) 24 9.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 15 Total number of positively charged residues (Arg + Lys): 20 Atomic composition: Carbon C 1194 Hydrogen H 1919 Nitrogen N 319 Oxygen O 304 Sulfur S 10 Formula: C1194H1919N319O304S10 Total number of atoms: 3746 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 26595 Abs 0.1% (=1 g/l) 1.026, assuming all pairs of Cys residues form cystines Ext. coefficient 26470 Abs 0.1% (=1 g/l) 1.021, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 29.32 This classifies the protein as stable. Aliphatic index: 127.76 Grand average of hydropathicity (GRAVY): 0.826