ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKMAVDDPTY GTPKIKRTAS SSSSIETTVT KLLMSTKHLL QVLTQWSKGT TSGRLVSDAY 

        70         80         90        100        110        120 
VQLGNDFKVV SKFFMHAKVD MSDVGDVPMA LRRVLEVTLR EPPSDETLNK HLPKIREIIV 

       130        140        150        160        170        180 
TLLDKLKVKQ AILKNMQQEH RISVKSHHQQ NPSFTSNLSL GSEGTREGTP LSSRKSSIVR 

       190        200        210        220        230        240 
DQRQSDSVEN SYGEKVNSTS TGTPSAQSAE ATLTKPRTNI KQNLKSNNAP NASDDDDALS 

       250        260        270        280        290        300 
QLKKGTNLQR RASKRYSAYH MAKLTNQSTT EAAAAAGLMT TPSPSMLHLE ETVRKSKLYG 

       310        320        330        340        350        360 
NNNNDDDRNI NSAENKGKSI DDVSKASPLA KTPLPIENVR ASPRRLSSVV TTSPDKAMNG 

       370        380        390        400        410        420 
TCPVFLRIGD KTKKCHVQLP TTKNALRLLF IERFAYSPGA NSFPDIYIMD PQYGVFYELE 

       430        440        450        460        470        480 
ELNLLDIKEG FVIELKLEEN PNNTIKEFID TVKMEISNSQ NDIIRHLKEM SFGSAISGKQ 

       490        500        510        520        530        540 
TEVLPQPGLE ANKHDLVGQN KKDDDKTIKD IQYELGKIKQ VHNINRSNIN ETIFNILRKV 

       550        560        570        580        590        600 
DNFKSLSFSA KNSSNRMYME KSQTELGDLS DTLLSKVDDL QDVIEIMRKD VAERRSQPAK 

       610        620        630        640        650        660 
KKLETVSKDL ENAQADVLKL QEFIDTEKPH WKKTWEAELD KVCEEQQFLT LQEELILDLK 

       670        680        690        700        710        720 
EDLGKALETF DLIKLCCEEQ EKNPSRSKSN PILPIMRPGT FNQVREQVMV AVQSLNPDHD 

       730        740        750        760        770        780 
SRVEAIDKAE KMWEMERKLK ASNEFDDELE NFVGNSNLKK SGGFEEVERI RKQKDEANLR 


AYFGPGFT 

References and documentation are available.

Number of amino acids: 788

Molecular weight: 88816.61

Theoretical pI: 7.62

Amino acid composition: 
Ala (A)  43	  5.5%
Arg (R)  38	  4.8%
Asn (N)  51	  6.5%
Asp (D)  52	  6.6%
Cys (C)   5	  0.6%
Gln (Q)  36	  4.6%
Glu (E)  62	  7.9%
Gly (G)  32	  4.1%
His (H)  14	  1.8%
Ile (I)  40	  5.1%
Leu (L)  75	  9.5%
Lys (K)  77	  9.8%
Met (M)  21	  2.7%
Phe (F)  24	  3.0%
Pro (P)  34	  4.3%
Ser (S)  72	  9.1%
Thr (T)  50	  6.3%
Trp (W)   4	  0.5%
Tyr (Y)  13	  1.6%
Val (V)  45	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 114
Total number of positively charged residues (Arg + Lys): 115

Atomic composition:

Carbon      C	      3867
Hydrogen    H	      6284
Nitrogen    N	      1098
Oxygen      O	      1239
Sulfur      S	        26

Formula: C3867H6284N1098O1239S26
Total number of atoms: 12514

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    41620
Abs 0.1% (=1 g/l)   0.469, assuming all pairs of Cys residues form cystines


Ext. coefficient    41370
Abs 0.1% (=1 g/l)   0.466, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.30
This classifies the protein as unstable.



Aliphatic index: 78.93

Grand average of hydropathicity (GRAVY): -0.697