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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKRGESQAPD AIFGQSRAFA LSDSSVNPDV IEYLKSVRQE ALRTNAISIK NHMNLQKRTR

70 80 90 100 110 120
HKSSMYDDED EGALKRHAIS PSLIRLQRNV EIWVRWFNSV KATVLTNAYE FTGYEDETLD

130 140 150 160 170 180
LLLLFLKNYL EDMPSKCTTV EKIISVLNQH SFPEKAEEKE ENLQIDEEWA KNILVRLEKT

190 200 210 220 230 240
KIDSVEDVKK VITEGDKHEL VGYNQWFQYL INNEPQHTTF HEKITSKQLW VLIKYMSNTW

250 260 270 280 290 300
IKEIHKKGRH YRRLQDWLFY ILVHTPERVT AEYTSILRDL GKKCLELIQK KPVEAHENKI

310 320 330 340
TLPKEMAELN VEIPAAVENM TITELTVSVI AVNYGQKDLI E


References and documentation are available.

Number of amino acids: 341 Molecular weight: 39859.60 Theoretical pI: 6.17
Amino acid composition: 
Ala (A) 18 5.3% Arg (R) 16 4.7% Asn (N) 19 5.6% Asp (D) 16 4.7% Cys (C) 2 0.6% Gln (Q) 14 4.1% Glu (E) 36 10.6% Gly (G) 9 2.6% His (H) 11 3.2% Ile (I) 26 7.6% Leu (L) 34 10.0% Lys (K) 31 9.1% Met (M) 7 2.1% Phe (F) 9 2.6% Pro (P) 10 2.9% Ser (S) 20 5.9% Thr (T) 21 6.2% Trp (W) 7 2.1% Tyr (Y) 12 3.5% Val (V) 23 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 52 Total number of positively charged residues (Arg + Lys): 47 Atomic composition: Carbon C 1786 Hydrogen H 2834 Nitrogen N 482 Oxygen O 532 Sulfur S 9 Formula: C1786H2834N482O532S9 Total number of atoms: 5643 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 56505 Abs 0.1% (=1 g/l) 1.418, assuming all pairs of Cys residues form cystines Ext. coefficient 56380 Abs 0.1% (=1 g/l) 1.414, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.71 This classifies the protein as unstable. Aliphatic index: 93.46 Grand average of hydropathicity (GRAVY): -0.525