ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKSSSSQSYD VFPNFRGEDV RHSLVSHLRK ELDRKFINTF NDNRIERSRK ITPELLLAIE 

        70         80         90        100        110        120 
NSRISLVVFS KNYASSTWCL DELVKIQECY EKLDQMVIPI FYKVDPSHVR KQTGEFGMVF 

       130        140        150        160        170        180 
GETCKGRTEN EKRKWMRALA EVAHLAGEDL RNWRSEAEML ENIAKDVSNK LFPPSNNFSD 

       190        200        210        220        230        240 
FVGIEAHIEA LISMLRFDSK KARMIGICGP SETGKTTIGR ALYSRLKSDF HHRAFVAYKR 

       250        260        270        280        290        300 
KIRSDYDQKL YWEEQFLSEI LCQKDIKIEE CGAVEQRLKH TKVLIVLDDV DDIELLKTLV 

       310        320        330        340        350        360 
GRIRWFGSES KIVVITQKRE LLKAHNIAHV YEVGFPSEEL AHQMFCRYAF GKNSPPHGFN 

       370        380        390        400        410        420 
ELADEAAKIA GNRPKALKYV GSSFRRLDKE QWVKMLSEFR SNGNKLKISY DELDGKGQDY 

       430        440        450        460        470        480 
VACLTNGSNS QVKAEWIHLA LGVSILLNIR SDGTTILKHL SYNRSMAQQA KIWWYENLER 

       490        500        510        520        530        540 
VCKKYNICGI DSSTDGGGST YGQCSNSQFQ RNMDASPGGN KTSNQSTKDS PRASQVEKEK 

       550        560        570        580        590        600 
IEYCEPHVYI TPAIFSDGTR APKYVESSSR RVTQVHHAKT WWPENCEKVY ENHNNIYGID 

       610        620        630        640        650        660 
RSIDGGDKFE GKSKVSDGGL DGKDQGSMYG QSSNSELQIN MDADNRRCEP VSEMLFKNYN 

       670        680        690        700        710        720 
VCSPNGLTDV NCSNPQSQRK LDASLKKDKI VHEWIRTGSG FFFDFQGPKS IVSAAQVDEK 

       730        740        750        760        770        780 
NFEYCEQGVY ITLGILSGGI IVLKHLEFSR RMAQQAKVWW SENWIKVYQE HNICGIDKSF 

       790 
DGRFDDRRVI RQLRPN 

References and documentation are available.

Number of amino acids: 796

Molecular weight: 91154.18

Theoretical pI: 8.56

Amino acid composition: 
Ala (A)  40	  5.0%
Arg (R)  50	  6.3%
Asn (N)  44	  5.5%
Asp (D)  47	  5.9%
Cys (C)  18	  2.3%
Gln (Q)  33	  4.1%
Glu (E)  59	  7.4%
Gly (G)  52	  6.5%
His (H)  21	  2.6%
Ile (I)  52	  6.5%
Leu (L)  56	  7.0%
Lys (K)  65	  8.2%
Met (M)  15	  1.9%
Phe (F)  34	  4.3%
Pro (P)  22	  2.8%
Ser (S)  73	  9.2%
Thr (T)  26	  3.3%
Trp (W)  15	  1.9%
Tyr (Y)  27	  3.4%
Val (V)  47	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 106
Total number of positively charged residues (Arg + Lys): 115

Atomic composition:

Carbon      C	      4023
Hydrogen    H	      6297
Nitrogen    N	      1145
Oxygen      O	      1212
Sulfur      S	        33

Formula: C4023H6297N1145O1212S33
Total number of atoms: 12710

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   123855
Abs 0.1% (=1 g/l)   1.359, assuming all pairs of Cys residues form cystines


Ext. coefficient   122730
Abs 0.1% (=1 g/l)   1.346, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.22
This classifies the protein as unstable.



Aliphatic index: 75.06

Grand average of hydropathicity (GRAVY): -0.606