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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKTVAALTLL AFATAANGQF LQDCTNALDG LYALGECEPQ FLTCSGGIAR IMDCPADLIY

70 80 90 100 110 120
NEPLLICDWR HNVIGCEGSG ESSGETSGEG SGESSGEASG EGSGEASGEG SGEASGEGSG

130 140 150 160 170 180
EASGEGSGSG EETVENVCEN LEDGAYSSGG CTTYYFFCTT NTARFLSCPT PLFYDADSQK

190 200 210 220 230 240
CIWKSLVEEC KEDLTITDGS GETSGEGSGE ASGEASGEGS GEASGESSGQ GSGEASGEGS

250 260 270 280 290 300
GELEPTCEGK ADGIHPNGVC STNFLTCSGG IARIMDCPAS LVFNPTILVC DWPRDVAECA

310 320 330 340 350 360
GLPTPQPTCE EDGYFSFGQC SSSFTACTNG RAIVMFCPAG LKFSESTVRC DYESNVSECQ

370 380 390 400 410 420
ETSGEESGEA SGEQSGEGSG EASGEASGES SGEGSGVEEQ NQCVGLDNGL HAIGCSPRVL

430 440 450 460 470 480
SCQNGHVDIF ECPSSLVFND QSLICDYPQT SLKCLIEDTI LIDETPIAAF DCSTDGLFSD

490 500 510 520
GLCSATYHQC TAGQLINFTC AASNAVFSAA NTECVDSSTL LQCH


References and documentation are available.

Number of amino acids: 524 Molecular weight: 53651.96 Theoretical pI: 3.84
Amino acid composition: 
Ala (A) 42 8.0% Arg (R) 8 1.5% Asn (N) 19 3.6% Asp (D) 26 5.0% Cys (C) 36 6.9% Gln (Q) 17 3.2% Glu (E) 58 11.1% Gly (G) 73 13.9% His (H) 6 1.1% Ile (I) 20 3.8% Leu (L) 35 6.7% Lys (K) 7 1.3% Met (M) 4 0.8% Phe (F) 20 3.8% Pro (P) 18 3.4% Ser (S) 68 13.0% Thr (T) 35 6.7% Trp (W) 3 0.6% Tyr (Y) 10 1.9% Val (V) 19 3.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 84 Total number of positively charged residues (Arg + Lys): 15 Atomic composition: Carbon C 2243 Hydrogen H 3442 Nitrogen N 606 Oxygen O 842 Sulfur S 40 Formula: C2243H3442N606O842S40 Total number of atoms: 7173 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 33650 Abs 0.1% (=1 g/l) 0.627, assuming all pairs of Cys residues form cystines Ext. coefficient 31400 Abs 0.1% (=1 g/l) 0.585, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.44 This classifies the protein as stable. Aliphatic index: 59.47 Grand average of hydropathicity (GRAVY): -0.235