ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MKVLDLLTVL SASSLLSTFA AAESTATADS TTAASSTASC NPLKTTGCTP DTALATSFSE 

        70         80         90        100        110        120 
DFSSSSKWFT DLKHAGEIKY GSDGLSMTLA KRYDNPSLKS NFYIMYGKLE VILKAANGTG 

       130        140        150        160        170        180 
IVSSFYLQSD DLDEIDIEWV GGDNTQFQSN FFSKGDTTTY DRGEFHGVDT PTDKFHNYTL 

       190        200        210        220        230        240 
DWAMDKTTWY LDGESVRVLS NTSSEGYPQS PMYLMMGIWA GGDPDNAAGT IEWAGGETNY 

       250        260        270        280        290        300 
NDAPFTMYIE KVIVTDYSTG KKYTYGDQSG SWESIEADGG SIYGRYDQAQ EDFAVLANGG 

       310        320        330        340        350        360 
SISSSSTSSS TVSSSASSTV SSSVSSTVSS SASSTVSSSV SSTVSSSSSV SSSSSTSPSS 

       370        380        390        400        410        420 
STATSSKTLA SSSVTTSSSI SSFEKQSSSS SKKTVASSST SESIISSTKT PATVSSTTRS 

       430        440        450        460        470        480 
TVAPTTQQSS VSSDSPVQDK GGVATSSNDV TSSTTQISSK YTSTIQSSSS EASSTNSVQI 

       490        500 
SNGADLAQSL PREGKLFSVL VALLALL 

References and documentation are available.

Number of amino acids: 507

Molecular weight: 52758.04

Theoretical pI: 4.46

Amino acid composition: 
Ala (A)  38	  7.5%
Arg (R)   6	  1.2%
Asn (N)  15	  3.0%
Asp (D)  31	  6.1%
Cys (C)   2	  0.4%
Gln (Q)  15	  3.0%
Glu (E)  19	  3.7%
Gly (G)  32	  6.3%
His (H)   3	  0.6%
Ile (I)  19	  3.7%
Leu (L)  30	  5.9%
Lys (K)  23	  4.5%
Met (M)   8	  1.6%
Phe (F)  15	  3.0%
Pro (P)  13	  2.6%
Ser (S) 123	 24.3%
Thr (T)  60	 11.8%
Trp (W)   7	  1.4%
Tyr (Y)  18	  3.6%
Val (V)  30	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 50
Total number of positively charged residues (Arg + Lys): 29

Atomic composition:

Carbon      C	      2262
Hydrogen    H	      3539
Nitrogen    N	       591
Oxygen      O	       839
Sulfur      S	        10

Formula: C2262H3539N591O839S10
Total number of atoms: 7241

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    65445
Abs 0.1% (=1 g/l)   1.240, assuming all pairs of Cys residues form cystines


Ext. coefficient    65320
Abs 0.1% (=1 g/l)   1.238, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.60
This classifies the protein as unstable.



Aliphatic index: 62.35

Grand average of hydropathicity (GRAVY): -0.304