ProtParam
User-provided sequence:
10 20 30 40 50 60
MKWKVLQLKT QEIKVNNLAK SSLHQPGSLV LRNRIRNNQT ISNHQKVYIT NLHKDKLKLN
70 80 90 100 110
NLLRLMKSTN RHMPFRNLVL ATGQELALLH NKRKRRKTLP LALFYSHLIL L
References and
documentation are available.
Number of amino acids: 111
Molecular weight: 13107.65
Theoretical pI: 11.75
Total number of negatively charged residues (Asp + Glu): 3
Total number of positively charged residues (Arg + Lys): 22
Atomic composition:
Carbon C 588
Hydrogen H 992
Nitrogen N 182
Oxygen O 150
Sulfur S 3
Formula: C
588H
992N
182O
150S
3
Total number of atoms: 1915
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.647
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 47.20
This classifies the protein as unstable.
Aliphatic index: 115.05
Grand average of hydropathicity (GRAVY): -0.474