ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLAAKNILNR SSLSSSFRIA TRLQSTKVQG SVIGIDLGTT NSAVAIMEGK VPKIIENAEG 

        70         80         90        100        110        120 
SRTTPSVVAF TKEGERLVGI PAKRQAVVNP ENTLFATKRL IGRRFEDAEV QRDIKQVPYK 

       130        140        150        160        170        180 
IVKHSNGDAW VEARGQTYSP AQIGGFVLNK MKETAEAYLG KPVKNAVVTV PAYFNDSQRQ 

       190        200        210        220        230        240 
ATKDAGQIVG LNVLRVVNEP TAAALAYGLE KSDSKVVAVF DLGGGTFDIS ILDIDNGVFE 

       250        260        270        280        290        300 
VKSTNGDTHL GGEDFDIYLL REIVSRFKTE TGIDLENDRM AIQRIREAAE KAKIELSSTV 

       310        320        330        340        350        360 
STEINLPFIT ADASGPKHIN MKFSRAQFET LTAPLVKRTV DPVKKALKDA GLSTSDISEV 

       370        380        390        400        410        420 
LLVGGMSRMP KVVETVKSLF GKDPSKAVNP DEAVAIGAAV QGAVLSGEVT DVLLLDVTPL 

       430        440        450        460        470        480 
SLGIETLGGV FTRLIPRNTT IPTKKSQIFS TAAAGQTSVE IRVFQGEREL VRDNKLIGNF 

       490        500        510        520        530        540 
TLAGIPPAPK GVPQIEVTFD IDADGIINVS ARDKATNKDS SITVAGSSGL SENEIEQMVN 

       550        560        570        580        590        600 
DAEKFKSQDE ARKQAIETAN KADQLANDTE NSLKEFEGKV DKAEAQKVRD QITSLKELVA 

       610        620        630        640        650 
RVQGGEEVNA EELKTKTEEL QTSSMKLFEQ LYKNDSNNNN NNNGNNAESG ETKQ 

References and documentation are available.

Number of amino acids: 654

Molecular weight: 70627.84

Theoretical pI: 5.48

Amino acid composition: 
Ala (A)  61	  9.3%
Arg (R)  30	  4.6%
Asn (N)  39	  6.0%
Asp (D)  37	  5.7%
Cys (C)   0	  0.0%
Gln (Q)  27	  4.1%
Glu (E)  52	  8.0%
Gly (G)  48	  7.3%
His (H)   3	  0.5%
Ile (I)  42	  6.4%
Leu (L)  49	  7.5%
Lys (K)  51	  7.8%
Met (M)   9	  1.4%
Phe (F)  23	  3.5%
Pro (P)  23	  3.5%
Ser (S)  47	  7.2%
Thr (T)  47	  7.2%
Trp (W)   1	  0.2%
Tyr (Y)   7	  1.1%
Val (V)  58	  8.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 89
Total number of positively charged residues (Arg + Lys): 81

Atomic composition:

Carbon      C	      3088
Hydrogen    H	      5052
Nitrogen    N	       868
Oxygen      O	      1000
Sulfur      S	         9

Formula: C3088H5052N868O1000S9
Total number of atoms: 10017

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.226

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.83
This classifies the protein as stable.



Aliphatic index: 89.31

Grand average of hydropathicity (GRAVY): -0.325