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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLCAISGKVP RRPVLSPKSR TIFEKSLLEQ YVKDTGNDPI TNEPLSIEEI VEIVPSAQQA

70 80 90 100 110 120
SLTESTNSAT LKANYSIPNL LTSLQNEWDA IMLENFKLRS TLDSLTKKLS TVMYERDAAK

130 140 150 160 170 180
LVAAQLLMEK NEDSKDLPKS SQQAVAITRE EFLQGLLQSS RDFVARGKLK APKWPILKNL

190 200 210 220 230 240
ELLQAQNYSR NIKTFPYKEL NKSMYYDKWV CMCRCEDGAL HFTQLKDSKT ITTITTPNPR

250 260 270 280 290 300
TGGEHPAIIS RGPCNRLLLL YPGNQITILD SKTNKVLREI EVDSANEIIY MYGHNEVNTE

310 320 330 340 350 360
YFIWADNRGT IGFQSYEDDS QYIVHSAKSD VEYSSGVLHK DSLLLALYSP DGILDVYNLS

370 380 390 400 410 420
SPDQASSRFP VDEEAKIKEV KFADNGYWMV VECDQTVVCF DLRKDVGTLA YPTYTIPEFK

430 440 450 460 470 480
TGTVTYDIDD SGKNMIAYSN ESNSLTIYKF DKKTKNWTKD EESALCLQSD TADFTDMDVV

490 500
CGDGGIAAIL KTNDSFNIVA LTP


References and documentation are available.

Number of amino acids: 503 Molecular weight: 56570.06 Theoretical pI: 5.03
Amino acid composition: 
Ala (A) 31 6.2% Arg (R) 17 3.4% Asn (N) 28 5.6% Asp (D) 37 7.4% Cys (C) 9 1.8% Gln (Q) 18 3.6% Glu (E) 33 6.6% Gly (G) 21 4.2% His (H) 5 1.0% Ile (I) 32 6.4% Leu (L) 50 9.9% Lys (K) 38 7.6% Met (M) 10 2.0% Phe (F) 15 3.0% Pro (P) 22 4.4% Ser (S) 44 8.7% Thr (T) 37 7.4% Trp (W) 6 1.2% Tyr (Y) 22 4.4% Val (V) 28 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 70 Total number of positively charged residues (Arg + Lys): 55 Atomic composition: Carbon C 2508 Hydrogen H 3958 Nitrogen N 654 Oxygen O 793 Sulfur S 19 Formula: C2508H3958N654O793S19 Total number of atoms: 7932 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 66280 Abs 0.1% (=1 g/l) 1.172, assuming all pairs of Cys residues form cystines Ext. coefficient 65780 Abs 0.1% (=1 g/l) 1.163, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.27 This classifies the protein as unstable. Aliphatic index: 85.88 Grand average of hydropathicity (GRAVY): -0.387