ProtParam
User-provided sequence:
10 20 30 40 50 60
MLEAKMVMVV PTIEDQAMIV LHPKILSQSV VMHIKGQNYQ LDLVKVKHIM IEVGHLDPQV
70 80 90 100 110 120
RTGAMVLIKG ITAYVKSIRK TVHNVHNYGF LKSHFKRAKT AAKPTLTKLH LTSATRLQKM
130 140 150 160 170 180
KKSRIKDSRR MKQLETNFKR KIIEIHEIAV LPIEPMKIKG TTEIERAILR RFRKVPRVGI
TSVGTRGNY
References and
documentation are available.
Number of amino acids: 189
Molecular weight: 21678.05
Theoretical pI: 10.68
Total number of negatively charged residues (Asp + Glu): 13
Total number of positively charged residues (Arg + Lys): 37
Atomic composition:
Carbon C 971
Hydrogen H 1640
Nitrogen N 284
Oxygen O 254
Sulfur S 10
Formula: C
971H
1640N
284O
254S
10
Total number of atoms: 3159
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.275
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 49.93
This classifies the protein as unstable.
Aliphatic index: 103.07
Grand average of hydropathicity (GRAVY): -0.206