ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLELIYILPL LCFVYFLFRR FVLENFYVES SGKYVMITGC DSGFGRLLAT SLLDKHVNVF 

        70         80         90        100        110        120 
AACFTQQGMA SLHSEWKLKK GPKGQLYTLQ LDVTSQASVD SAKSFVTKIL KEQNSKLWGL 

       130        140        150        160        170        180 
VNNAGIFSIH GPDDWCSVDE YASSLNVNTL GAVRMCHAFV PLIKKSRGRI VTMGSTAGRL 

       190        200        210        220        230        240 
HGLYVAPYVT AKFAVEAYMD CLRLEMRPFG VSVHILEPGC FKTELLNNDA QRMRIQKIWN 

       250        260        270        280        290        300 
SLSVETKEEY GEDYRNDFER AWEAGVNVVA NPNIGWVVDC YSHALFSWWP RLRYCPGWDA 

       310        320        330        340        350        360 
IFMFIPLSIF PTALQDWILA GLYKLNPGPS LTPAVLVKNK KRRSAIQWIQ FLSQIAIIPL 

       370        380 
LYTIFFVKNT QKQTVETSTH HHNVTVSE 

References and documentation are available.

Number of amino acids: 388

Molecular weight: 44079.16

Theoretical pI: 8.83

Amino acid composition: 
Ala (A)  26	  6.7%
Arg (R)  17	  4.4%
Asn (N)  18	  4.6%
Asp (D)  14	  3.6%
Cys (C)   9	  2.3%
Gln (Q)  14	  3.6%
Glu (E)  18	  4.6%
Gly (G)  23	  5.9%
His (H)  10	  2.6%
Ile (I)  22	  5.7%
Leu (L)  42	 10.8%
Lys (K)  22	  5.7%
Met (M)   9	  2.3%
Phe (F)  22	  5.7%
Pro (P)  16	  4.1%
Ser (S)  28	  7.2%
Thr (T)  20	  5.2%
Trp (W)  11	  2.8%
Tyr (Y)  15	  3.9%
Val (V)  32	  8.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 32
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      2020
Hydrogen    H	      3108
Nitrogen    N	       524
Oxygen      O	       548
Sulfur      S	        18

Formula: C2020H3108N524O548S18
Total number of atoms: 6218

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    83350
Abs 0.1% (=1 g/l)   1.891, assuming all pairs of Cys residues form cystines


Ext. coefficient    82850
Abs 0.1% (=1 g/l)   1.880, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.70
This classifies the protein as stable.



Aliphatic index: 94.95

Grand average of hydropathicity (GRAVY): 0.057