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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLETLRGNKL HSGTSKGANK KLNELLESSD NLPSASSELG SIQVSINELR RRVFQLRSKN

70 80 90 100 110 120
KASKDYTKAH YLLANSGLSF EDVDAFIKDL QTNQFLEPNP PKIIESEELE FYIRTKKEEN

130 140 150 160 170 180
ILMSIEQLLN GATKDFDNFI NHNLNLDWAQ HKNEVMKNFG ILIQDKKTVD HKKSISSLDP

190 200 210 220 230 240
KLPSWGNKGN NILNSNESRL NVNENNILRE KFENYARIVF QFNNSRQANG NFDIANEFIS

250 260 270 280 290 300
ILSSANGTRN AQLLESWKIL ESMKSKDINI VEVGKQYLEQ QFLQYTDNLY KKNMNEGLAT

310 320 330 340 350 360
NVNKIKSFID TKLKKADKSW KISNLTVING VPIWALIFYL LRAGLIKEAL QVLVENKANI

370 380 390 400 410 420
KKVEQSFLTY FKAYASSKDH GLPVEYSTKL HTEYNQHIKS SLDGDPYRLA VYKLIGRCDL

430 440 450 460 470 480
SRKNIPAVTL SIEDWLWMHL MLIKEKDAEN DPVYERYSLE DFQNIIISYG PSRFSNYYLQ

490 500 510 520 530 540
TLLLSGLYGL AIDYTYTFSE MDAVHLAIGL ASLKLFKIDS STRLTKKPKR DIRFANILAN

550 560 570 580 590 600
YTKSFRYSDP RVAVEYLVLI TLNEGPTDVE LCHEALRELV LETKEFTVLL GKIGRDGARI

610 620 630 640 650 660
PGVIEERQPL LHVRDEKEFL HTITEQAARR ADEDGRIYDS ILLYQLAEEY DIVITLVNSL

670 680 690 700 710 720
LSDTLSASDL DQPLVGPDDN SETNPVLLAR RMASIYFDNA GISRQIHVKN KEICMLLLNI

730 740 750 760 770 780
SSIRELYFNK QWQETLSQME LLDLLPFSDE LSARKKAQDF SNLDDNIVKN IPNLLIITLS

790 800 810 820 830
CISNMIHILN ESKYQSSTKG QQIDSLKNVA RQCMIYAGMI QYRMPRETYS TLINIDVSL


References and documentation are available.

Number of amino acids: 839 Molecular weight: 96173.86 Theoretical pI: 6.38
Amino acid composition: 
Ala (A) 45 5.4% Arg (R) 38 4.5% Asn (N) 67 8.0% Asp (D) 49 5.8% Cys (C) 5 0.6% Gln (Q) 33 3.9% Glu (E) 59 7.0% Gly (G) 32 3.8% His (H) 15 1.8% Ile (I) 69 8.2% Leu (L) 108 12.9% Lys (K) 65 7.7% Met (M) 15 1.8% Phe (F) 30 3.6% Pro (P) 23 2.7% Ser (S) 72 8.6% Thr (T) 36 4.3% Trp (W) 8 1.0% Tyr (Y) 34 4.1% Val (V) 36 4.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 108 Total number of positively charged residues (Arg + Lys): 103 Atomic composition: Carbon C 4302 Hydrogen H 6848 Nitrogen N 1156 Oxygen O 1298 Sulfur S 20 Formula: C4302H6848N1156O1298S20 Total number of atoms: 13624 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 94910 Abs 0.1% (=1 g/l) 0.987, assuming all pairs of Cys residues form cystines Ext. coefficient 94660 Abs 0.1% (=1 g/l) 0.984, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.18 This classifies the protein as unstable. Aliphatic index: 100.08 Grand average of hydropathicity (GRAVY): -0.365