ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLGKEEEQQY GQNGKGMENE LPFMKRPWFK KAYENAIEFH EKDELLDARD RLELSKAYRS 

        70         80         90        100        110        120 
IAKAEMWGGW LGFSAVFLTP FAYRYYKTKA IKGVKVPRNF VLGVMALFFA TNFAGRSMYT 

       130        140        150        160        170        180 
RQLNERDPTG VLKDNYSNKY GDNDFGAFQH DQTKEIPRNQ RQYNMMRLLD SGSPSRWSMY 

       190        200        210        220        230        240 
FYITYQNPER RLPDPKVKLQ QMKKGGVFNG SPFMNQRDPI GLYRNKGRKS PDPIEGEQND 

       250        260        270        280        290        300 
SPVLSSWEKI RNGDNSSSSS WENIRNTSRD QSQESDASVD HESDIFISGF SDDGNATDNS 

       310        320 
SSDDKYQRLL QSGRYGGNRS 

References and documentation are available.

Number of amino acids: 320

Molecular weight: 36946.04

Theoretical pI: 8.92

Amino acid composition: 
Ala (A)  15	  4.7%
Arg (R)  24	  7.5%
Asn (N)  23	  7.2%
Asp (D)  23	  7.2%
Cys (C)   0	  0.0%
Gln (Q)  17	  5.3%
Glu (E)  20	  6.2%
Gly (G)  26	  8.1%
His (H)   3	  0.9%
Ile (I)  11	  3.4%
Leu (L)  20	  6.2%
Lys (K)  23	  7.2%
Met (M)  11	  3.4%
Phe (F)  17	  5.3%
Pro (P)  15	  4.7%
Ser (S)  31	  9.7%
Thr (T)   9	  2.8%
Trp (W)   6	  1.9%
Tyr (Y)  16	  5.0%
Val (V)  10	  3.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 43
Total number of positively charged residues (Arg + Lys): 47

Atomic composition:

Carbon      C	      1624
Hydrogen    H	      2479
Nitrogen    N	       467
Oxygen      O	       503
Sulfur      S	        11

Formula: C1624H2479N467O503S11
Total number of atoms: 5084

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    56840
Abs 0.1% (=1 g/l)   1.538

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.35
This classifies the protein as unstable.



Aliphatic index: 51.53

Grand average of hydropathicity (GRAVY): -1.020