ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLGRRAVSVH RFLSRAARQS VTAASSAQPS LQAKTSLLEP LVQNVRITSS ANFHMSAVRM 

        70         80         90        100        110        120 
SDVITVEGPA FAESISEGDI RWLKQKGDHV NEDELVAEIE TDKTSVEVPA PQAGTIVEFL 

       130        140        150        160        170        180 
VEDGAKVTAK QKLYKLQPGA GGGSSSAPAK EEPKSAPAKE ESKPAPAKED SKPAVTAAAP 

       190        200        210        220        230        240 
PKPVSGDIPK SAPPVARPPS TPSSSTPVGA VPVTRVVVPK GVDPSHAITG ARDEVRVKAN 

       250        260        270        280        290        300 
RMRMRIAQRL KDAQNTYAML TTFNEIDMSS LIEMRKTYQK DFVAKHGVKL GMMSPFVRAA 

       310        320        330        340        350        360 
AYALQESPVV NAVLDENEIV YRHFVDISVA VATPKGLVVP VLRNVESMNY AQIELELANL 

       370        380        390        400        410        420 
GVKARDGKLA VEDMEGGTFT ISNGGVFGSM FGTPIINPPQ SAILGMHGVF DRVVPVNGKP 

       430        440        450        460 
EIRPIMQIAL TYDHRLIDGR EAVTFLKKIK TAVEDPRIMF MNL 

References and documentation are available.

Number of amino acids: 463

Molecular weight: 49813.34

Theoretical pI: 9.08

Amino acid composition: 
Ala (A)  52	 11.2%
Arg (R)  26	  5.6%
Asn (N)  15	  3.2%
Asp (D)  21	  4.5%
Cys (C)   0	  0.0%
Gln (Q)  15	  3.2%
Glu (E)  30	  6.5%
Gly (G)  29	  6.3%
His (H)   8	  1.7%
Ile (I)  24	  5.2%
Leu (L)  28	  6.0%
Lys (K)  30	  6.5%
Met (M)  17	  3.7%
Phe (F)  14	  3.0%
Pro (P)  36	  7.8%
Ser (S)  36	  7.8%
Thr (T)  24	  5.2%
Trp (W)   1	  0.2%
Tyr (Y)   7	  1.5%
Val (V)  50	 10.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 56

Atomic composition:

Carbon      C	      2198
Hydrogen    H	      3576
Nitrogen    N	       618
Oxygen      O	       663
Sulfur      S	        17

Formula: C2198H3576N618O663S17
Total number of atoms: 7072

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.320

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 51.84
This classifies the protein as unstable.



Aliphatic index: 86.35

Grand average of hydropathicity (GRAVY): -0.169