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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLHCARRYML VRPRLLWQSG TCVARFQSSV RTPASEPSAE KGVDEWLEAI NELREEFSAK

70 80 90 100 110 120
EYLPETSLAP PGQSKVDLLQ GSQAGSKIKP TAEQLAQWEA LKSVPIPPRK NATLDHITNM

130 140 150 160 170 180
IMRHGKKEKA QTILSRALYL VYCQTRQDPI QALEKSLDEL APLMMTKTFN TGVAKASVIP

190 200 210 220 230 240
VPLNKRQRNR IAWNWIVQSA NQRVSSDFAV RLGEELTAIA KGTSSAFEKR DQIHKTAIAH


RAYIQLK


References and documentation are available.

Number of amino acids: 247 Molecular weight: 27816.10 Theoretical pI: 9.76
Amino acid composition: 
Ala (A) 27 10.9% Arg (R) 18 7.3% Asn (N) 8 3.2% Asp (D) 7 2.8% Cys (C) 3 1.2% Gln (Q) 16 6.5% Glu (E) 17 6.9% Gly (G) 9 3.6% His (H) 5 2.0% Ile (I) 14 5.7% Leu (L) 24 9.7% Lys (K) 18 7.3% Met (M) 6 2.4% Phe (F) 5 2.0% Pro (P) 14 5.7% Ser (S) 19 7.7% Thr (T) 14 5.7% Trp (W) 5 2.0% Tyr (Y) 5 2.0% Val (V) 13 5.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 24 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1230 Hydrogen H 1996 Nitrogen N 358 Oxygen O 358 Sulfur S 9 Formula: C1230H1996N358O358S9 Total number of atoms: 3951 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 35075 Abs 0.1% (=1 g/l) 1.261, assuming all pairs of Cys residues form cystines Ext. coefficient 34950 Abs 0.1% (=1 g/l) 1.256, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.21 This classifies the protein as unstable. Aliphatic index: 86.19 Grand average of hydropathicity (GRAVY): -0.433