Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLHCTQVCLS ALTKRTHRVK VQVLKDFPRF QLYKGQVANV KPSLMRNYLH NFNGAKYILS

70 80 90 100 110 120
EEHDINTELL KQYQTLEAKL EEDHQQLSKR HETEVQKNME LRKESVFGHK KEEKPKEEKK

130
GLLDSGITIE EVKIPGLDI


References and documentation are available.

Number of amino acids: 139 Molecular weight: 16282.78 Theoretical pI: 8.79
Amino acid composition: 
Ala (A) 4 2.9% Arg (R) 6 4.3% Asn (N) 6 4.3% Asp (D) 5 3.6% Cys (C) 2 1.4% Gln (Q) 9 6.5% Glu (E) 16 11.5% Gly (G) 6 4.3% His (H) 7 5.0% Ile (I) 6 4.3% Leu (L) 17 12.2% Lys (K) 18 12.9% Met (M) 3 2.2% Phe (F) 4 2.9% Pro (P) 4 2.9% Ser (S) 6 4.3% Thr (T) 7 5.0% Trp (W) 0 0.0% Tyr (Y) 4 2.9% Val (V) 9 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 21 Total number of positively charged residues (Arg + Lys): 24 Atomic composition: Carbon C 721 Hydrogen H 1172 Nitrogen N 204 Oxygen O 214 Sulfur S 5 Formula: C721H1172N204O214S5 Total number of atoms: 2316 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 6085 Abs 0.1% (=1 g/l) 0.374, assuming all pairs of Cys residues form cystines Ext. coefficient 5960 Abs 0.1% (=1 g/l) 0.366, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.80 This classifies the protein as unstable. Aliphatic index: 86.19 Grand average of hydropathicity (GRAVY): -0.797