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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MLHVGEESFQ MSTLLERTKS VQELKKRAAG KTSANPAEVA KAKKVLRRLY SWDEIPEWQR

70 80 90 100 110 120
DNDFILHGYV KETSSFIETF KSLFYLHNES VNIYSHLIPA LGFFTVLLLD KSTIKVFATT

130 140 150 160 170 180
TWLDHMVIDL FYSGAFACLI LSSSFHCLKS HSLRIATLGN KLDYLGICIL IVTSMVSILY

190 200 210 220 230 240
YGYFEKFSLF CLFALITVSF GIACSIVSLK DKFRKREWRP YRAGLFVCFG LSSIIPIFSG

250 260 270 280 290 300
LYCYSFSEIW TQIQLFWVLL GGVLYIIGAV LYGMRFPEKI CPGKFDIWGH SHQLFHFLVV

310 320
IAALCHLRGL LNSYELVHIK MENGIVS


References and documentation are available.

Number of amino acids: 327 Molecular weight: 37437.08 Theoretical pI: 8.85
Amino acid composition: 
Ala (A) 17 5.2% Arg (R) 12 3.7% Asn (N) 7 2.1% Asp (D) 9 2.8% Cys (C) 9 2.8% Gln (Q) 6 1.8% Glu (E) 16 4.9% Gly (G) 20 6.1% His (H) 12 3.7% Ile (I) 28 8.6% Leu (L) 44 13.5% Lys (K) 20 6.1% Met (M) 6 1.8% Phe (F) 26 8.0% Pro (P) 7 2.1% Ser (S) 31 9.5% Thr (T) 14 4.3% Trp (W) 7 2.1% Tyr (Y) 15 4.6% Val (V) 21 6.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1753 Hydrogen H 2683 Nitrogen N 427 Oxygen O 451 Sulfur S 15 Formula: C1753H2683N427O451S15 Total number of atoms: 5329 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 61350 Abs 0.1% (=1 g/l) 1.639, assuming all pairs of Cys residues form cystines Ext. coefficient 60850 Abs 0.1% (=1 g/l) 1.625, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.28 This classifies the protein as stable. Aliphatic index: 109.69 Grand average of hydropathicity (GRAVY): 0.415